Introduction The Department of Physiology and Cell Biology, an integral part of the basic medical sciences division at the University of Health Sciences, with a strong interdisciplinary approach, focuses on developing and delivering quality postgraduate programs. The Department provides an excellent environment for postgraduate studies, attempts to integrate molecular, cellular and systems approaches to physiological sciences. The Department offers PhD program and an MPhil program leading to PhD degree.

Dr.Khalid Parvez Lone Professor and Head of Department M.Sc. (Pb.), M.I. Biol. (London), Ph.D. (Birmingham)F.Z.S.P. E-mail : kplone@uhs.edu.pk

• The department is looking forward to proceed 3 to 4 M.Phil students for Ph.D. degree each year.
• The UHS is developing a state-of-the-art Endocrinology & Reproductive science centre under the umbrella of HEC to provide backup research in reproductive health and metabolic dysfunctions especially in the local context. The centre shall house core facilities for research involving PCR, immunoassay, radioimmunoassay, IVF, Karyotyping and imaging.

Research Activities

• One Ph.D. and nine M.Phil students have successfully completed and defended their thesis.
• At present five Ph.D. and 14 M.Phil students are working on different research projects.

Research Projects
Projects completed: M.Phil. (Session 2004)

• Family History as a Risk Factor for the Onset of Type 2 Diabetes in a Sample of Local Population
  Dr. Adeela Shahid
• A Study of Pubertal Development and Growth among Boys in a Sample of Local Population
  Dr. Asima Karim
• Y Chromosomal Micro Deletions in a Local Infertile Male Population
  Dr. Ayesha Siddique
• Proteomic Analysis of Ovarian Cystic Fluid and Serum and Possible identification of Protein Biomarkers
  Dr. Gulfam Ahmad
• Endicrine accompaniments in patients with nonfunctioning pituitary adenoma before and after surgery
  Dr. Saba Khalid
• Dispersion of QT Interval in Uncomplicated Obesity
  Dr. Sadia Zafar
• Breast Cancer Risk Association with BRCA1 and BRCA2 Mutation in a Local Population of Females Diagnosed with Breast Cancer
  Dr. Samina Malik
• Polycystic Ovary Syndrome and its Association with Cardiovascular Risk Factors and Serum Insulin Level Index
  Dr. Tanzeela Akram

Projects completed: M.Phil. (Session 2005)

• Serum oxidized LDL and C-Reactive Protein as Indicator of Early Atherosclerosis in Type-I Diabetic Children
  Dr. Aqeela Hamad Butt
• Folate Metabolism in Migraine: Association of Plasma Homocysteine with C677T Variant of Methylenetetrahydrofolate Reductase (MTHFR) gene in migraine
  Dr. Faraz Ahmed Bokhari

Projects in hand: M.Phil. (Session 2004)

• Seasonal Variations and Effect of Temperature on Serum and Tissue Lipid Profile in a Poikilotherm Vertebrate, Uromastyx Hardwicki
  Dr.Ghazala Qureshi
• Effect of Exogenous Platelet Activating Factor on Sperm Capacitation and Acrosome Reaction in Infertile Male Patients
  Dr.Qamar Shakoor

Projects in hand: M.Phil. (Session 2005)

• Red Blood Cell Changes in Helicobacter Pylori Infected Cases
  Dr. Saqib Sohail
• Contribution of Male Factor Infertility in a Sample of Local Population
  Dr. Ambreen Khalid
• Age Related Changes in Bone Mineral Density, Bone Maturation and Bone Remodeling Markers in Type I Diabetic Children
  Dr. Amina Tahir
• Changes in Peripheral Inflammatory Mediators in Chronic Periodontitis
  Dr. Ayesha Anwar

Projects in hand: M.Phil. (Session 2006)

• Mannose-Binding Lectin and its Correlation With Serum Testosterone at Puberty in Type I Diabetic Boys
  Dr. Amer Shoaib
• Association of Serum Visfatin With Body Fat Distribution and Dyslipidemia in Obese Adolescents Of a Local Population
  Dr. Bushra Hussain
• Serum Inflammatory Markers in Obese Teenager and the Relative Prevalence Periodontal Disease
  Dr. Mubashar ul Hassan
• Dysregulation of Pituitary-Gonadal Axis in Male Offspring of Type 2 Diabetic Parents
  Dr. M.Ijaz Anwar
• Adrenal Gland Function in Natives of Cholistan Desert
  Dr.Shazia Sultan

Projects in hand: M.Phil. (Session 2007)

• Comparison of Waist Circumference and Body Mass Index as Predictors of Pulmonary Function Boys
  Dr. Sohail Atta-ur-Rasool
• Relationship of Thyroid Function in the Low Normal Range With Metabolic Syndrome
  Dr. Shahzad Saleem

Projects in hand: M.Phil. (Session 2008)

• Comparative Study of Serum Anti-Citrullinated Protein Antibody and Rheumatoid Factor for Diagnosing Rheumatoid Arthritis Boys
  Dr. Bushra Gohar Shah
• Serum Hyaluronic Acid as Biomarker of Disease Severity in Osteoarthritis
  Dr. Imran
• Predictive Role of Pulmonary Function Test among asymptomatic Rheumatoid Lung Disease Patients
  Dr. Izaz-ur-Rehman
• Comparative Study of Non-Invasive Parameters in Predicting and Grading Esophageal Varices
  Dr. Syeda Zainab
• VDRL Polymorphism (Fok1, Bsm1) and Breast Cancer Risk in Pakistani Population
  Dr. Merium Mubarak
• Iron Stores and Insulin Resistance in Healthy Offspring of Type-2 Diabetics
  Dr. Uzma Zargham

Ph.D.

• Genetic Variants in the Leptin, Leptin Receptor and FTO Genes in Obese Pakistani Population
  Dr. Adeela Shahid
• Growth, Obesity and Pubertal Development Pattern in School Girls of Province of Punjab
  Dr. Asima Karim
• Molecular Markers of Susceptibility to Prion Diseases in Local Humans and Domesticated Bovids
  Mr. M. Imran
• Expression of Circadian Clock and Cell Cycle Genes in Chronic Lymphocytic Leukemia
  Ms. Sobia Rana