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  • Research Activities
  • Research Publications
  • Faculty

Introduction


Overview of Department
The Department of Physiology & Cell Biology, an integral part of the basic medical sciences division at the University of Health Sciences, with a strong interdisciplinary approach, focuses on developing and delivering quality postgraduate programs. The Department provides an excellent environment for postgraduate studies, attempts to integrate molecular, cellular and systems approaches to physiological sciences. It also promote research interaction with public agencies and industry through outreach and scientific leadership; organize symposia, seminars and special lectures in relevant disciplines at national and international levels.

The Department offers PhD program and an MPhil program leading to PhD degree. The teaching in the department is committed to bring changes to the traditional teaching practices and takes full advantage of advanced audio-visual systems both in lectures and Lab exercises which include Power lab experiments. In additions to the regular teaching, the students regularly attend tutorials, journal club meetings and informal discussion on the topics that need further explorations. Every student is supposed to present latest papers/studies, published in international journals, and related to his/her thesis. Also, every student of the M.Phil. (primary) presents his/her hypothesis on which he/she is going to write their synopsis and when ready, at least, two presentations are given by the respective student which are discussed very extensively and new point arising out of these discussion are incorporated which increases the acceptability and scientific merit of the synopsis to be submitted to Advanced Studies and Research Board of the University. Similarly, the students of the final year keep on reporting on the results obtained during their research work and these are also discussed and ideas for explanation and discussion evolving during these discussions help the candidate a lot in presentation of the final thesis of the students. In order to give exposure to teaching and lab conduction, the final year students are involved in running the labs along with the faculty. This practice helps the students to hone and polish their skills in teaching and demonstrations.

The postgraduate program at UHS aspires to higher education and research training in selected areas of Physiology and Cell Biology. Specializations areas are:
  • Molecular and Cell Physiology
  • Metabolic Biochemistry
  • Systemic Physiology
  • Endocrinology
  • Reproductive and Developmental Biology
  • Environmental Physiology
Working Facilities

The Department has three well established Labs and centers namely Main Physiology Lab, Resource Lab for Molecular & Cell Biology and Centre of Research in Endocrinology and Reproductive Sciences. Currently, the laboratories are well-equipped with modern research facilities for DNA studies, proteomics, immunoassay, radioimmunoassay, DNA sequencing analysis, Karyotyping, and blood and tissue chemistry. Instruments like Immunofluorescence and inverted research microscopes, HPLC, bone profiler, Horizontal and Vertical electrophoresis, and biosafety laminar flow cabinets are continuously used for various research experiments.

The Department also possesses a good-sized departmental library.

Research Activities

Being an integral part for the award of MPhil and PhD degrees, all students undertake research in different fields of Physiology. Major research interest of Physiology & Cell Biology Department are:

  • Vitamin D Prevalence in Pakistani Population
  • Vitamin D association with different metabolic disorders
  • Vitamin D receptor genetics
  • Diabetes, Metabolic Syndrome and Insulin Resistance
  • PCOs and Endometriosis
  • Bone Health and Nutrition
  • COPD and Respiratory disorders
  • Reproductive Biology of Male Gamete
  • HCV Pathogenesis and related Physiological Issues
  • Dengue Infection and interaction with Host-genes
  • Ovarian cancer proteomics
  • Gestational Diabetes Mellitus
  • Myocardial infarction

Research funding

The research work performed at Department of Physiology is funded by different agencies like HEC, PMRC and PSF in addition to University of Health Sciences, Lahore.

1. Research Projects sponsored by Higher education commission, Pakistan (HEC)

  • Serum Somatostatin 1GF-1 and insulin Resistance in Patients of Polycystic Ovarian Syndrome and in Healthy Females of Rs 241,230/-
  • Correlation between homocysteine, Vitamin D, Vitamin B12, Folate and Bone Health in Postmenopausal Pakistani Women of Rs.762, 721/-
  • Serum Vitamin D Level and VDR polymorphism (Fok-1, and BSM-1) in type 1 Diabetics of local population of Rs.440,197/-
  • Arsenic and lead in serum and breast milk in female agricultural farm workers of Bahawalpur of Rs.294,847/-
  • Endometriosis and its association with TP53 gene (Codon 72) polymorphism in Lahore Rs.244,459/-
  • Comparative Study of Serum Anti-Citrullinated Protein Antibody and Rheumatoid Factor for Diagnosing Rheumatoid Arthritis Boys Rs.182541/-
  • Role of Anti-Cyclic Citrullinated Peptide Antibody and Anti-Mutated Citrullinated Vimentin Antibody in Diagnosing Rheumatoid Factor Negative Rheumatoid Arthritis Patients of Rs. 231621/-
  • Serum Vitamin D Level and VDR polymorphism (Fok-1, and BSM-1) in type 1 Diabetics of local population of Rs. 440197/-
  • A study of genetic variations in cytokines and TLRs genes and their expression level in association with dengue pathogenesis of Rs. 1763920/-

2. Projects sponsored by Pakistan Medical research council (PMRC)

  • Early Onset Of Renal Function Decline And Its Correlation With Serum Uric Acid In Diabetic Nephropathy of Rs. 48000/-
  • Serum Hyaluronic Acid as Biomarker of Disease Severity in Osteoarthritis Rs.48000/-
  • Effect of Breast and Bottle Feeding on Bone Growth in Prepubertal Children Rs.170,500/-

Seminars and workshops:

"Centre of research in endocrinology and reproductive sciences" at Department of Physiology & Cell Biology, University of Heath Sciences Lahore arranged a Seminar on 12 July, 2012. The seminar was entitled as "Vitamin D and Reproductive Health" by Professor Dr. Lubna Pal, Program Director Polycystic Ovarian syndrome/reproductive aging and bone. Yale Reproductive endocrinology Program, Yale University, USA.

Research Publications


Research publication:

Department of Physiology & Cell Biology

AKRAM, T., HASAN, S., IMRAN, M., KARIM, A. & ARSLAN, M.2009. Association of polycystic ovary syndrome with cardiovascular risk factors. Gynecol Endocrinol, 26, 47-53. https://www.tandfonline.com/doi/abs/10.3109/09513590903159565

MALIK, S., HANIF, A., KHOKHER, S., IQBAL, Z., RANA, S., IMRAN, M., BILAL, M. & ARSLAN, M. 2009. Association of genetic and non-genetic risk factors with specific BRCA mutation positive breast cancers in some Pakistani females. Pakistan Journal of Physiology, 5. https://pjp.pps.org.pk/index.php/PJP/article/view/836

KARIM, A. & AFZAL, M. N. 2009. Pubertal development and growth among boys in a sample of local Pakistani population. Acta Endocrinologica (Buc), 5, 165-174. https://www.researchgate.net/publication/233406697_Pubertal_development_and_growth_among_boys_in_a_sample_of_local_Pakistani_population

SALEEM, M., TABASSUM, M. R., YASMIN, R. & IMRAN, M. 2009. Potential of xylanase from thermophilic Bacillus sp. XTR-10 in biobleaching of wood kraft pulp. International Biodeterioration & Biodegradation, 63, 1119-1124. https://kundoc.com/pdf-potential-of-xylanase-from-thermophilic-bacillus-sp-xtr-10-in-biobleaching-of-wo.html

AFZAL, S., SALEEM, M., YASMIN, R., NAZ, M. & IMRAN, M. 2010. Pre and post cloning characterization of a ?-1, 4-endoglucanase from Bacillus sp. Bacillus sp. Mol. Biol. Rep., 37, 1717-1723. https://link.springer.com/article/10.1007%2Fs11033-009-9592-5

FATIMA, W., SHAHID, A., IMRAN, M., MANZOOR, J., HASNAIN, S., RANA, S. & MAHMOOD, S. 2011. Leptin deficiency and leptin gene mutations in obese children from Pakistan. Int J Pediatr Obes, 6, 419-427. https://www.ncbi.nlm.nih.gov/pubmed/21854111

HUSSAIN, A., BABAR, M. E., IMRAN, M., HAQ, I. U. & JAVED, M. M.2011. Detection of four novel polymorphisms in PrP gene of Pakistani sheep (Damani and Hashtnagri) and goats (Kamori and Local Hairy) breeds. Virology journal, 8, 246. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120785/

IMRAN, N., CHAUDRY, M. R., AZEEM, M. W., BHATTI, M. R., CHOUDHARY, Z. I. & CHEEMA, M. A.2011. A survey of Autism knowledge and attitudes among the healthcare professionals in Lahore, Pakistan. BMC pediatrics, 11. https://bmcpediatr.biomedcentral.com/articles/10.1186/1471-2431-11-107

RANA, S., WAHEED, I. & IMRAN, M.2011. Specific post-transcriptional inhibition of mRNA for ligand binding chain of IgE high affinity receptor. Mol. Biol. Rep., 38, 675-681. https://www.researchgate.net/publication/26757572_Specific_post-transcriptional_inhibition_of_mRNA_for_ligand_binding_chain_of_IgE_high_affinity_receptor

ZAFAR, U., QURESHI, H. J. & KARIM, A.2011. Insulin resistance and serum parameters of iron status in type 2 diabetics. Pak J Physiol, 7. http://pps.org.pk/PJP/7-2/Uzma.pdf

BABAR, M. E., HUSSAIN, T., IMRAN, M., NAGARAJAN, M. & KUMAR, S.2012. Mitochondrial DNA diversity patterns in Pakistani buffalo. Animal genetics, 43, 315-317. https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2052.2011.02250.x

BUGVI, S. M., IMRAN, M., MAHMOOD, S., HAFEEZ, R., FATIMA, W. & SOHAIL, S.2012. Screening of intron 1 inversion and three intragenic factor VIII gene polymorphisms in Pakistani hemophilia A families. Blood Coagulation & Fibrinolysis, 23, 132-137. https://journals.lww.com/bloodcoagulation/Fulltext/2012/03000/Screening_of_intron_1_inversion_and_three.4.aspx

IMRAN, M., SAEED, M. T., MAHMOOD, S., MOHSIN, S., SOHAIL, S., MUNIR, A. & NAZIR, H.2012. A strategy for carrier detection in Pakistani haemophilia B families. Haemophilia, 18, e348-e349. https://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1365-2516.2012.02860.x

MAHMOOD, U., IMRAN, M., NAIK, S. I., CHEEMA, H. A., SAEED, A., ARSHAD, M. & MAHMOOD, S.2012. Detection of common mutations in the GALT gene through ARMS. Gene, 509, 291-4. https://qbpatologica.files.wordpress.com/2013/06/2012-detection-of-common-mutations-in-the-galt-gene-through-arms.pdf

IMRAN, M., MAHMOOD, S., BABAR, M. E., HUSSAIN, R., YOUSAF, M. Z., ABID, N. B. & LONE, K. P. 2012. PRNP gene variation in Pakistani cattle and buffaloes. Gene, 505, 180-185. https://ac.els-cdn.com/S0378111912006269/1-s2.0-S0378111912006269-main.pdf?_tid=34327994-4673-4286-bef0-426ccd33a015&acdnat=1548662723_210a1ac10621b2b442effc14743ee033

IMRAN, M., MAHMOOD, S., HUSSAIN, R., ABID, N. B. & LONE, K. P.2012. Frequency distribution of PRNP polymorphisms in the Pakistani population. https://www.ncbi.nlm.nih.gov/pubmed/22062631

SHAHID, A., SAEED, S., RANA, S. & MAHMOOD, S.2012. Family history of diabetes and parental consanguinity: important risk for impaired fasting glucose in South East Asians. West Indian Medical Journal, 61, 219-223. https://www.ncbi.nlm.nih.gov/pubmed/23155976

ANSAR, T., TAHIR, M., LONE, K. P. & MUNIR, B.2013. Immunolocalization of Aquaporin-10 in Tuberculous Human Ileum. J Coll Physicians Surg Pak, 23, 392-396.

https://www.researchgate.net/publication/239061531_Immunolocalization_of_Aquaporin-10_in_Tuberculous_Human_Ileum

FAHEEM, M. & LONE, K. P.2013. Acute toxicity and Behavioural response of Cirrhinus mrigala fingerlings to Bisphenol-A. International Journal of Open Scientific Research IJOSR Vol.1, No. 6, 28-37 KINDI PUBLICATIONS https://s3.amazonaws.com/academia.edu.documents/37648684/IJOSR-1113-5.pdf?AWSAccessKeyId=AKIAIWOWYYGZ2Y53UL3A&Expires=1548672190&Signature=yO%2BZj9EoqDJHJLlh8j3JaHYi3HE%3D&response-content-disposition=inline%3B%20filename%3DAcute_toxicity_and_Behavioural_response.pdf

LIAQAT, I., JAHAN, N., LONE, K. P., PAKSTIS, A. & TAYLOR, H. S.2013. Genetic polymorphisms associated with endometriosis in Pakistani women. Journal of Endometriosis, 5, 134-143. https://journals.sagepub.com/doi/abs/10.5301/je.5000165

RANA, S., SHAHID, A., SAEED, S. & IQBAL, M. N.2013. Comparison of Thyroid Function Tests by RIA/IRMA Based Commercial Kit and in House Method in Hypothyroid Patients. Annals of King Edward Medical University, 18, 180-190 https://www.google.com/search?client=firefox-b-ab&q=Comparison+of+Thyroid+Function+Tests+by+RIA%2FIRMA+Based+Commercial+Kit+and+in+House+Method+in+Hypothyroid+Patients.+Annals+of+King+Edward+Medical+University%2C+18%2C+180-190.

SHAHID, A., RANA, S., SAEED, S., IMRAN, M., AFZAL, N. & MAHMOOD, S.2013. Common Variant of FTO Gene, rs9939609, and Obesity in Pakistani Females. BioMed research international,1.730, 01-08. https://www.hindawi.com/journals/bmri/2013/324093/

SIDDIQI, H., TAHIR, M. & LONE, K. P.2013. Variations in cerebral arterial circle of Willis in adult Pakistani population. J Coll Physicians Surg Pak, 23, 615-619. https://www.ncbi.nlm.nih.gov/pubmed/24034183

GUL, A., LONE, K. P. & AHMED, A.2014. Implications of umbilical cord blood serum in clinical applications. The Health, 4, 71-75. https://www.researchgate.net/publication/263973078_Implications_of_umbilical_cord_blood_serum_in_clinical_applications

HUMAYUN, F., TAHIR, M., LONE, K. P., MUNIR, B., AHMAD, A. L. I. & LATIF, W.2014. Protective Effect Of Ethanolic Extract Of Propolis On Isoniazid Induced Hepatotoxicity In Male Albino Mice. Biomedica, 30, 85-91. https://pdfs.semanticscholar.org/48e7/d348b03f0887380cd0805a083c42af578da7.pdf

ROOMI, M. A., LONE, K. P. & MADASSAR, A.2014. Vitamin D and cardiometabolic risk factors in adult non-diabetic offspring of type 2 diabetic parents. J Pak Med Assoc, 64, 1229-1234. https://www.ncbi.nlm.nih.gov/pubmed/25831636

RANA, S., MUNAWAR, M., SHAHID, A., MALIK, M., ULLAH, H., FATIMA, W., MOHSIN, S. & MAHMOOD, S.2014. Deregulated expression of circadian clock and clock-controlled cell cycle genes in chronic lymphocytic leukemia. Mol. Biol. Rep., 41, 95-103. https://www.ncbi.nlm.nih.gov/pubmed/24190490

SAEED, K., TAHIR, M., AND LONE, K.P.2015. Effect of Phoenix dactyliferia (date palm) pit powder on nicotine induced spermatotoxicty in adult albino mice. J. Pak. Med. Assoc., 65: 43-48. https://www.ncbi.nlm.nih.gov/pubmed/25831673

ROOMI, M.A., FAROOQ, A., ULLAH, E. AND LONE, K.P.2015. Serum vitamin D levels and the components of metabolic syndrome: an analytical cross-sectional study. Rawal Med. J., 40: 2-6. https://www.researchgate.net/publication/282374742_Serum_vitamin_D_levels_and_the_components_of_metabolic_syndrome_An_analytical_cross-sectional_study

FAHEEM, M., JAHAN N., LONE K.P.2015. Histopathological Effects of Bisphenol-A on Liver, Kidneys and Gills of Indian Major Carp, Catla catla (Hamilton, 1822). J. Ani. Vet. Sci. Fish-15-0009 http://www.thejaps.org.pk/docs/v-26-02/29.pdf

RASHID, M.U., MERIUM MUZAFFAR.2015. Association between the BsmI Polymorphism in the Vitamin D Receptor Gene and Breast Cancer Risk: Results from a Pakistani Case-Control Study. PLOS ONE. DOI: 10.1371/journal.pone.0141562. https://www.ncbi.nlm.nih.gov/pubmed/26517870

NAZIR, S., LONE, K.P., AHMAD, G.2015. Women diagnosed with endometriosis possess high body mass index compared to controls. Pak. J. Med & Health Sci. July-Sep 2015 https://www.researchgate.net/publication/305528378_Women_diagnosed_with_endometriosis_possess_high_body_mass_index_compared_to_controls

CHEEMA, M. A AND LONE, K.P.2016. Quantitative ultrasound bone profile and vitamin D status in 5-11 years old children with intellectual disability. J Pak Med Assoc. 2016. June. 66(6). https://www.ejmanager.com/mnstemps/33/33-1421317027.pdf?t=1548747125

NASREEN M., LONE, K. P., KHALIQ, S., KHALIQ, S.2016. Serum Vitamin D levels and Vitamin D receptor (VDR) gene polymorphism (Fok I and Apa I) in Type I diabetes. J Pak Med Assoc. 2016 Oct;66(10):1215-1220. http://jpma.org.pk/full_article_text.php?article_id=7922

ASLAM, R., RAZA, SM., NAEEMI, H., MUBARAK, B., AFZAL, N., KHALIQ, S.2016. SOCS3 mRNA expression and polymorphisms as pre-treatment predictor of response to HCV genotype 3a IFN-based treatment. Springerplus. 2016 Oct 21;5(1):1826. https://springerplus.springeropen.com/articles/10.1186/s40064-016-3506-5

ASHFAQ, U.A., IQBAL, M.S., KHALIQ, S.2016. Role of Toll-like receptors in hepatitis C infection and treatment. Crit Rev Eukaryot Gene Expr. 2016;26(4):353-362. http://www.dl.begellhouse.com/journals/6dbf508d3b17c437,73c57fd25a6798d9,0cea633633de4d7a.html

MANZOOR S., AKHTAR, U., NASEEM, S., KHALID, M, MAZHAR, M., PERVAIZ, F., KHALIQ, S.2016. Ionotropic Purinergic Receptors P2X4 and P2X7: Proviral or Antiviral? An Insight into P2X Receptor Signaling and HCV Infection. Viral Immunol. 2016 Sep;29(7):401-8. doi: 10.1089/vim.2016.0008. https://www.liebertpub.com/doi/abs/10.1089/vim.2016.0008?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

AKBAR, S., JAHAN, S., BASHIR, S., KHALIQ, S., AFTAB, I., FAIZAN, M., HUSSAIN, S., MOHSIN, S.2017. Frequency of BCR/ABL-1 Fusion Gene and Deletion IKZF- 1 in Acute Lymphoblastic Leukemia Patients. IJMAR, 2(1), 2017; 10-16.

GHANI, M.U., HAQUE, A., QASIM, M., ASHFAQ, U.A., IQBAL, M.S., WAHEED, A., AFZAL, N., SAEED, F., MASOUD, M.S., KHALIQ, S., JAHAN, S.2017. Involvement of vascular endothelial growth factor (VEGF) gene polymorphism in hepatocellular carcinoma of HCV patients from local population. Pure and applied Biology 6(2): 725-732, June 2017. http://www.thepab.org/index.php/journal/article/view/131

KHALIQ S., NAEEMI H., ASLAM, R.2017. Polymorphism in Interleukin genes: Predictive of non-response or relapse in HCV genotype 3a patients. Abstracts of the 26th Annual Conference of APASL, February 15-19, 2017, Shanghai, China. Hepatology International. February 2017, Volume 11, Supplement 1, pp 1-1093. (page 1037-38). https://link.springer.com/article/10.1007%2Fs12072-016-9783-9

AFTAB, I., IRAM, S., KHALIQ, S., ISRAR, M., ALI, N., JAHAN, S., HUSSAIN, S., KHALIQ, S., MOHSIN, S.2017. Analysis of FANCC gene mutations (IVS4+4A>T, DEL322G, R548X) in patients of fanconi anemia in Pakistan. Turk J Med Sci. 2017 Apr 18;47(2):391-398. doi: 10.3906/sag-1506-53. https://www.ncbi.nlm.nih.gov/pubmed/28425259

AYMUN, U., IRAM, S., AFTAB, I., KHALIQ, S., ALI, N., AHMED, N., MOHSIN, S.2017. Screening for mutations in two exons of FANCG gene in Pakistani population. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2017, 161(2):158-163 | 10.5507/bp.2017.030. http://biomed.papers.upol.cz/artkey/bio-201702-0006_screening_for_mutations_in_two_exons_of_fancg_gene_in_pakistani_population.php

KHALID, A., SARFRAZ, B., MANZOOR, S., SAALIM, M., KHALIQ, S.2017. PTEN: A Potential prognostic marker in virus-induced Hepatocellular Carcinoma". Tumor Biology 39(6):101042831770575 . June 2017. DOI: 10.1177/1010428317705754. http://journals.sagepub.com/doi/abs/10.1177/1010428317705754?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed&

MUBARAK, B., AFZAL, N., TALIB, R., ASLAM, R., JAVAID, K., LATIFE, W., KHALIQ, S.2017. Frequency of HLA DQ?1*0201 and DQ?1*0301 Alleles and Total Serum IgE in Patients with Bronchial Asthma: A Pilot Study from Pakistan. Iranian Journal of Allergy, Asthma and Immunology 2017. 16(4):313-320. http://ijaai.tums.ac.ir/index.php/ijaai/article/view/896

SHAHZAD, A., KHALIQ, S., AMMAR, A., MAHMOOD, S.2017. Metachromatic leukodystrophy (MLD): A Pakistani family with novel ARSA gene mutation. J Mol Neurosci. 63(1), 84-90 doi: 10.1007/s12031-017-0959-0. [Epub ahead of print] https://link.springer.com/article/10.1007%2Fs12031-017-0959-0

IQBAL, M. S., ASHFAQ, U.A., KHALIQ, S., GHANI, M.U., HAQUE, A., MASOUD, M.S., AWAN, M.Q., JAHAN, S.2017. Toll like receptor 4 polymorphism as pretreatment predictor of response to HCV genotype 3a IFN-based treatment. Future Virology 27 Nov 2017. 12(12): 739-746. doi.org/10.2217/fvl-2017-0076. https://www.futuremedicine.com/doi/10.2217/fvl-2017-0076

FAHEEM, M., KHALIQ, S., LONE, K.P. 2017. Non-monotonic endocrine disrupting effect of bisphenol-A on vitellogenin expression in juvenile freshwater cyprinid, Catla catla. Pakistan J. Zool., 49(4), 1531-1534, 2017. DOI: http://dx.doi.org/10.17582/journal.pjz/2017.49.4.sc9. http://www.bioone.org/doi/abs/10.2108/zs170009

FAHEEM, M., KHALIQ, S., AHMAD, H.U., LONE, K.P.2017. Bisphenol-A (BPA) alters plasma thyroid hormones and sex steroids in female Pakistani major carp (Catla catla; Cyprinidae). Pak Vet J, 2017. 37(3): 326-330. http://www.pvj.com.pk/pdf-files/37_3/326-330.pdf

FAHEEM, M., KHALIQ, S., LONE, K.P.2017. Disruption of reproductive axis in fresh water fish, Catla catla, after bisphenol-A exposure. Zoological Science, 2017, Oct;34(5):438-444. doi: 10.2108/zs170009. http://www.bioone.org/doi/10.2108/zs170009?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed&

FAHEEM, M., JAHAN, N., KHALIQ, S., LONE, K.P.2017. Validation of reference genes for expression analysis in a teleost fish (Catla catla Hamilton) exposed to an endocrine-disrupting chemical, Bisphenol-A. RENDICONTI LINCEI-SCIENZE FISICHE E NATURALI, 2017.1-10. Doi:10.1007/s12210-017-0653-8. https://link.springer.com/article/10.1007/s12210-017-0653-8

ZAKIR A, LONE, K.P., RAZA, M.S., KHALIQ, S AND JAHAN, S.2018. Transcriptome analysis of Apoptotic markers in peripheral blood mononuclear cells of HCV genotype-3a infected Patients. Ind. J. gasterol. JPMI VOL. 32 NO. 2 April 26, 2018 JPMI VOL. 32 NO. 2 April 26, 2018. https://www.jpmi.org.pk/index.php/jpmi/article/download/2207/2019

FAHEEM, M., JAHAN, N., KHALIQ, S., LONE, KP.2018. Modulation of brain Kisspeptin expression after exposure to bisphenol-A in a teleost fish (Catla catla). Fish Physiol Biochem (2018). July 3. https://doi.org/10.1007/s10695-018-0532-y. https://link.springer.com/article/10.1007%2Fs10695-018-0532-y

HUSSAIN, R., KHALIQ S., RAZA, S. M., KHALIQ S., LONE, K.P.2018. Association of TP53 codon 72 polymorphism in women suffering from endometriosis from Pakistan. J Pak Med Assoc. 2018: 68 (2): 224-230. http://jpma.org.pk/full_article_text.php?article_id=8558

ZAFAR, U., KHALIQ, S., USMAN, H., MANZOOR, S., LONE, K.P.2018. Metabolic Syndrome: An Update on Diagnostic Criteria, Pathogenesis and Genetic Links. Hormones 2018 Sep;17(3):299-313. doi: 10.1007/s42000-018-0051-3. Epub 2018 Aug 31. https://link.springer.com/article/10.1007%2Fs42000-018-0051-3#citeas

AHMAD, M., HAMEED, A., KHALIQ, S., SAEED, H., MOHSIN, S.2018. Frequency of TEL-AML1 fusion gene in patients of Acute Lymphoblastic Leukemia. Annals of King Edward Medical University, 24(1): 1, Apr. 2018. http://www.annalskemu.org/journal/index.php/annals/article/view/2337

PERVAIZ, A., AKHTAR, M.S., MAHMOOD, S., SAJJAD, O., KHALIQ, S., BERGER, M.R.2018. Molecular basis of cell cycle arrest induced by erufosine in metastatic breast cancer cells [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14-18; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 4307. http://cancerres.aacrjournals.org/content/78/13_Supplement/4307

KHALIQ, S., RAZA, SM.2018. Current situation of Direct Acting Antiviral agents (DAAs) against HCV in Pakistan. Medicina (Kaunas). 2018 Nov 5;54(5). pii: E80. doi: 10.3390/medicina54050080. https://www.mdpi.com/1010-660X/54/5/80

ASLAM, N., BATOOL, F., IQBAL, M.S., ASHFAQ, U.A., AYAZ, S., KHALIQ, S., JAHAN, S., GHANI, M.U., USMAN, M.2018. Analysis of toll-like receptors-9 (TLR9) gene polymorphism (rs5743836) in Pakistani patients with HCV. Pak. J. Pharm. Sci., November 2018, 31:(6-Suppl), 2709-2714. http://www.pjps.pk/wp-content/uploads/pdfs/31/6/Supplementary/20-SUP-963.pdf

IQBAL, MS., ASHFAQ, UA., ASLAM, S., KHALIQ, S., GHANI, M,U., BATOOL., F.2018. Analysis of Polymorphism rs1990760 of IFIH1 gene and Treatment Outcomes in HCV infection. Future Virol. 1 Feb 2018. 13(2): 181-87 DOI: 10.2217/fvl-2017-0116. https://www.futuremedicine.com/doi/10.2217/fvl-2017-0116

NAEEMI, H., ASLAM, R., RAZA, S.M., SHAHZAD, M.A., NAZ, S., MANZOOR, S., KHALIQ, S.2018. Distribution of IL28B and IL10 polymorphisms as genetic predictors of treatment response in Pakistani HCV genotype 3 patients. Arch Virol, April 2018,163 (4); 997-1008. https://link.springer.com/article/10.1007%2Fs00705-018-3711-3

YOUSAF, M., JUNAID, K., IQBAL, MS., ASLAM, I., AHMAD, S., AQEEL, M., ASHFAQ, UA., KHALIQ, S., GHANI, U., WAQAR, N.2018. Analysis of Dengue virus burden and Serotypes pattern in Faisalabad, 2016 to 2017. Future Virol 2018 13:4, 245-251. https://doi.org/10.2217/fvl-2017-0155. https://www.futuremedicine.com/doi/10.2217/fvl-2017-0155

NIDA, LONE KP. Plasma surfactant protein-A levels in apparently healthy smokers, stable and exacerbation COPD patients. Pak J Med Sci. 2018;34(4):934-939. doi:10.12669/pjms.344.13951. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115589/

Tariq S, Tariq S, Lone KP. Interplay of vitamin D, vitamin B12, homocysteine and bone mineral density in postmenopausal females. Health Care Women Int. 2018 Dec;39(12):1340-1349. doi: 10.1080/07399332.2018.1444042, Epub 2018 Mar 20.

NAZIR S, USMAN Z, IMRAN M, LONE KP, AHMAD G. Women Diagnosed with Endometriosis Show High Serum Levels of Diethyl Hexyl Phthalate. J Hum Reprod Sci. 2018 Apr-Jun;11(2):131-136. doi: 10.4103/jhrs.JHRS_137_17.

ZAFAR, U., KHALIQ, S., USMAN, H.M., LONE, K.P. Serum profile of cytokines and their genetic variants in metabolic syndrome. Bioscience Reports Feb 01, 2019, 39 (2) BSR20181202;DOI: https://doi.org/10.1042/BSR20181202. http://www.bioscirep.org/content/39/2/BSR20181202

FAHEEM M., KHALIQ, S., LONE, KP. Effect of Bisphenol-A on serum - biochemistry and Liver Function in the Freshwater Fish, Catla catla. Pak Vet J, 2019, 39(1): 71-75. DOI: http://dx.doi.org/10.29261/pakvetj/2019.003 http://www.pvj.com.pk/in_press/17-406.pdf

ALI, Z., KHALIQ, S., ZAKI, S., AHMAD, H.U., LONE, K.P. Differential Expression of Placental Growth Factor, Transforming Growth Factor-? and Soluble Endoglin in Peripheral Mononuclear Cells in Preeclampsia. J Coll Physicians Surg Pak 2019, Vol. 29 (3): 235-239. https://jcpsp.pk/archive/2019/Mar2019/10.pdf

TARIQ, S., TARIQ, S., LONE, K.P., KHALIQ, S. Alkaline phosphatase is a predictor of Bone Mineral Density in postmenopausal females. Pak J Med Sci. 2019;35(3): 749-753. https://doi.org/10.12669/pjms.35.3.188. http://pjms.org.pk/index.php/pjms/article/view/188

ALI, Z., KHALIQ, S., ZAKI, S., AHMAD, H.U., LONE, K.P. Altered expression of vascular endothelial growth factor, vascular endothelial growth factor receptor?1, vascular endothelial growth factor receptor?2, and Soluble Fms-like Tyrosine Kinase-1 in peripheral blood mononuclear cells from normal and preeclamptic pregnancies. Chin J Physiol 2019;62:117-22. DOI: 10.4103/CJP.CJP_15_19. http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2019;volume=62;issue=3;spage=117;epage=122;aulast=Ali

ZAFAR, U., KHALIQ, S., LONE, K.P. Genetic association of Apolipoprotein A5 -1131T>C polymorphism with different traits of metabolic syndrome. J Coll Physicians Surg Pak. 2019 Jul;29(7):626-630. doi: 10.29271/jcpsp.2019.07.626. https://jcpsp.pk/archive/2019/Jul2019/08.pdf

TALIB, R., KASHIF, M., TAHIR, R., AHMED, N., KHALIQ, S., MUBARIK, B., ABBAS, A., JAHAN, S., & AFZAL, N. (2019). Association of interleukin-6 polymorphism (-634C/G) in the promoter region with diabetic nephropathy in type 2 diabetes mellitus. Bangla J Med Sci, 18(4), 741-747. https://doi.org/10.3329/bjms.v18i4.42878.

ZAFAR, U., KHALIQ, S., USMAN, H.M., LONE, K.P. Peroxisome proliferator activated receptor gamma 34C>G varaints and anthropometric parameters in metabolic syndrome. 2019. 8. J Pak Med Assoc. 69 (9): 1259-1265. https://www.jpma.org.pk/article-details/9307

KHAN RA, WASEEM HM, AHMAD HU, LONE KP. Plasma surfactant Protein-D levels in healthy subjects and COPD patients. J Pak Med Assoc. 2019 Apr;69(4):494-498. https://jpma.org.pk/article-details/9110?article_id=9110

Faculty



Prof. Dr. Fridoon Jawad Ahmad
  • Head of Department
  • BS, Genetics (UW Madison, USA), PhD Cell & Molecular Biology, UW Madison, USA

Dr. Asima Karim
  • Associate Professor
  • MBBS (Pb), M.Phil. (UHS), Ph.D

Dr. Saba Khaliq
  • Associate Professor
  • M.Sc. (GCU), Ph.D. (Pb), Post-doc. (Germany)

Dr. Asma Salam
  • Lecturer
  • MBBS (Punjab), MS (Netherlands)
Laboratory Staff

Hafiz Usman Ahmad
  • Senior Lab Manager Quality Control Management
  • M.Phil. (MLS) Chemical Pathology Cont. University of Health Sciences Lahore

Ms. Rubina Sheikh
  • Senior Lab Technologist.
  • M.Sc. Molecular Biology & Biotechnology The school of Allied Health Sciences Medical Technology Laboratory Lahore
Supporting Staff

Qadeer-uz-Zaman
  • Department Assistant
  • Department of Physiology & Cell Biology, University of Health Sciences Lahore.

H.M. Nasir Ali
  • Office Helper
  • Department of Physiology & Cell Biology, University of Health Sciences Lahore.

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