UHS-Dept

Research Activities

Session 2005-2007

1. Immunohistochemical Expression of Histidine Decarboxylase and Cytokeratin 19 and its correlation with histological grading in primary lung carcinomas by Dr. Nadia Naseem (Awarded Degree)

Session 2006 2008

1. Expression of HER 2/neu and its correlation with the histological grading of colorectal carcinomaby Dr. Sadia Anwar (Awarded Degree)

2. Study of Ki-67 labeling index with grading and staging of colorectal carcinoma. By Dr. Uzma Nabi (Awarded Degree)

3. Correlation of Estrogen Receptor expression with the Ki-67 proliferative index in carcinoma of the breast by Dr. Mahwish Hussain (Awarded Degree)

4. Immunohistochemical expression and correlation of Mammaglobin with Scarf-Bloom Richardson grading system of breast carcinoma by Dr. Fakeha Rehman(Awarded Degree)

5. Expression of Bcl-2 oncoprotein in uterine leiomyomata as an apoptosis inhibitor. By Dr. Seema Butt(Awarded Degree)

Session 2007 - 2009

1. Diagnostic role of CD117 in small cell carcinoma of lung by Dr. Sobia Sadiq(Awarded Degree)

2. A Morphological Study of Muscular Dystrophies and the Role of Dystrophin in their Diagnosis by Dr. Saira Sajid(Awarded Degree)

3. Morphological Study of Placenta in Pre-eclampsia and Eclampsia by Dr. Maham Akhlaq(Awarded Degree)

Session 2008 - 2010

1. Morphological study of Round Blue Cell Tumors of Childhood and their classification.

By Dr. Muneeza Khalid (Awarded Degree)

2. Morphology of Hirschsprung’s Disease in suction and full thickness rectal biopsies By

Dr. Nausheen Henna (Awarded Degree)

Session 2009 – 2011

1. Morphology of Hepatitis C Virus Associated Nephropathy and Expression of Anti HCV-NS3 by Dr. Munazza Chaudhary (Awarded Degree)

2. Morphology of IgA &Henoch-Schonlein Nephropathies-the role of immunofluorescence & iNO by Dr. Atika Masood (Awarded Degree)

3. Expression of p63 and S-100A6 in the Differentiation of KeratinocyticTumours of Skin by Dr. Usman Shams(Awarded Degree)

4. Morphology of Benign Proliferative Breast Lesions in the Mestectomy Specimens.

By Dr. SumeraQazi (Awarded Degree)

5. Morphological Study of Renal Lesions in Systemic Lupus Erythematosis by Dr. Fatima Rashid(Awarded Degree)

Session 2010 - 2012

1. Correlation of Mast Cell and Microvascular Density in Carcinoma of Lung by

Dr. Ehsan Ullah (Awarded Degree)

2. Smoking Related Interstitial Fibrosis and Interstitial Lung Disease: An Autopsy Study by Dr. Raees Abbas(Awarded Degree)

3. Morphological changes in liver and kidney of rodents induced by indigenous preparation of gold by Dr. Saadia Raza(Awarded Degree)

4. Mercury Kushta induced morphological changes in liver and kidney of rats by

Dr. Sakina Jamil (Awarded Degree).

Session 2011 -2013

1. Clininopathological Pattern and Classification of Breast Carcinoma based on ER/PR and HER2/ neu Immunohistochemistry by Dr. Farwa Batool(Awarded Degree)

2. Effects of Cadmium Salt on Kidney Tissue of White Rats by Dr. Nasim Aslam (Awarded Degree)

Session 2012 - 2014

1. Expression of minichromosome maintenance 2 and Ki-67 as proliferation markers in Renal cell carcinomaby Dr. M. Zain Mehdi(Awarded Degree)

2. Effects of Copper Preparations on Kidneys of Albino Rats by Dr. Hira Kareem (Awarded Degree)

3. Expression of TAMS and M2 Macrophages in Different Histological Grades of Breast Carcinoma by Dr. Nushmia Baig (Awarded Degree).

4. Expression of Isocitrate Dehydrogenase I and internexin alpha in gliomas by Dr. Irfan Basheer (Awarded Degree).

Session 2013 - 2015

1. Expression of NGAL in Class I-V Lupus Nephritis Using Immunohistochemical and Immunofluorescent Techniques by Dr. Sobia Khalid (Awarded Degree).

2. Effects of Arsenic Preparations on Kidney and Testes of Wister Rats by Dr. Sadaf Shafique (Awarded Degree).

3. Expression of Ki-67 & P53 as a Prognostic Marker in Wilms’ Tumour by Dr. Qurat Ul Ain (Awarded Degree).

4. Detection of DNA Mismatch Repair Antibodies AMS2 MSH6 MSH2 MLH1 in Carcinoma of Breast by Dr. Hadia Rafique (Awarded Degree)

Session 2014-16

1. Lead Kushta Induced Morphological Changes in Kidney of Rats by Dr. Rizwan Rasul (M.Phil part 1 exam clearance pending)

Session 2015-2017

1. Immunohistochemistry of H. pylori, characterization of its different serological strains and histological grading of chronic gastritis by Dr. Ayesha Suleman (Awarded Degree)

2. Immunohistochemical Expression of Interleukin-30 in Prostate Cancer by Dr. Azka Iqbal (Thesis submitted)

3. Detection of Mycobacterium Tuberculosis in Patients with Lymph Node TB by Immunohistochemistry and Indirect Immunofluorescence Techniques by Wajeeha Arooj (Research in Progress).

4. Detection of Mycobacterium Tuberculosis through Immunocytochemistry & Immunofluorescence from Cervical Lymph node Aspirates by Iqra Ijaz (M.Phil Cytotechnology) (Thesis submitted).

5. Detection of H. Pylori and MLH1 Gene Expression Analysis by Polymerase Chain Reaction in Patients of Chronic Gastritis with and without H.Pylori by Gulam Rasool (Degree Awarded).

6. Detection of Mycobacterium Tuberculosis in Formalin Fixed Parrafin Embedded Tissues through Ziehl-Neelsen Stain and PCR.by Raza Abbas (Degree awarded).

7. Hirschsprung’s Disease and the Role of Calretinin in Rectal Biopsies by Dr. Mishal Sikandar (Awarded Degree).

8. Protective Effect of Ginger on alcohol Induced Steatotic Liver of Rats by Dr. Muhammad Rashid (Awarded Degree).

9. Detection of Helicobacter Pylori through Histochemistryand ImmunofluorescentStaining in Biopsies of Patients with Chronic Gastritis byAsia Rao (Degree Awarded).

10. Comparative determination of integrity of RNA in experimental tissues fixed in formalin, universal molecular fixative and honey by Ayesha Saeed (Project taken over by department).

11. Immunohistochemical Expression and Association of Gata3 with ER Status and Nottingham Grading System of Breast Carcinoma by Dr. Iram Asrar (Degree Awarded).

12. Immunohistochemically Expression of Secreted Protein Acidic and Rich in Cysteine (SPARC) in Biopsies of Patients with Primary Breast Carcinoma of Different Histologic Grades and Clinical Stages by Dr. Waqas Arshad Mughal (Thesis work completed).

13. “Diagnostic Utility of Manual Liquid-based Cytology (MLBC) and Cell Block Preparation in Fine Needle Aspiration Cytology (FNAC) Specimens” by Ahsan Iqbal (Writing Synopsis).

14. Comparative Determination of Integrity of DNA in Experimental Tissues Fixed in Formalin, Universal molecular Fixative and Honey by Nida Ali Ahmed (Thesis writing in progress)

Session 2016-2018

Classification of cervical cytological lesions in HIV positive patients according to Bethesda system 2014 by Dr. Sobia Idrak (Thesis work completed)

Session 2017-2019

1. Cervical Cytological Changes in Relation with herpes Simplex Virus 1&2 in Pregnant Females of Local Population by Dr. Kainat Farrukh (Thesis Submitted)

2. Expression of Isocitrate Dehydraogenase-! In Gliomas Presenting in Local Population by Dr. Muntaha Masood (Thesis Submitted)

3. Cytological Changes in Relation with Human Papilloma in Patients with Oral Potentially Malignant Lisions by Dr. Maham Javed (Thesis Submitted)

4. Comparative antigenic determination on frozen section by Michel’s Transport medium and direct freezing methods by Mr. Tuaha Amjad ( Synopsis Approved)

Session 2018-2020

Cytokeratin 5 Expression on Immunohistochemistry by using Cell Block and Immnocytochemistry by using Liquid Based Cytology by Miss Sumaira Niaz (Thesis writing in progress)

Session 2019-2021

1. Dr. Shameen Fatima Shoaib (First Year in Progress)

2. Miss. Gulfishan Zameer (First Year in Progress)

3. Dr. Humaira Javed (First Year in Progress)

YEAR WISE ENROLLMENT OF M.PHIL. STUDENTS

Year

Students’ Name

Research Title

Status

Session 2005-2007

Dr. Nadia Naseem

Immunohistochemical Expression of Histidine Decarboxylase and Cytokeratin 19 and its correlation with histological grading in primary lung carcinomas

· Awarded Degree

Session 2006-2008

Dr. Sadia Anwar

Expression of HER 2/neu and its correlation with the histological grading of colorectal carcinoma

· Awarded Degree

Dr. Uzma Nabi

Study of Ki-67 labeling index with grading and staging of colorectal carcinoma.

· Awarded Degree

Dr. Mahwish Hussain

Correlation of Estrogen Receptor expression with the Ki-67 proliferative index in carcinoma of the breast

• Awarded Degree

Dr. Fakeha Rehman

Immunohistochemical expression and correlation of Mammaglobin with Scarf-Bloom Richardson grading system of breast carcinoma

· Awarded Degree

Dr. Seema Butt

Expression of Bcl-2 oncoprotein in uterine leiomyomata as an apoptosis inhibitor

· Awarded Degree

Session 2007-2009

Dr. Sobia Sadiq

Diagnostic role of CD117 in small cell carcinoma of lung

· Awarded Degree

Dr. Saira Sajid

A Morphological Study of Muscular Dystrophies and the Role of Dystrophin in their Diagnosis

· Awarded Degree

Dr. Maham Akhlaq

Morphological Study of Placenta in Pre-eclampsia and Eclampsia

· Awarded Degree

Session 2008-10

Dr. Muneeza Khalid

Morphological study of Round Blue Cell Tumors of Childhood and their classification.

· Awarded Degree

Dr. Nausheen Henna

Morphology of Hirschsprung’s Disease in suction and full thickness rectal biopsies

· Awarded Degree

Session 2009 – 2011

Dr. Munazza Chaudhary

Morphology of Hepatitis C Virus Associated Nephropathy and Expression of Anti HCV-NS3

· Awarded Degree

Dr. Atika Masood

Morphology of IgA &Henoch-Schonlein Nephropathies-the role of immunofluorescence & iNO

· Awarded Degree

Dr. Usman Shams

Expression of p63 and S-100A6 in the Differentiation of KeratinocyticTumours of Skin

· Awarded Degree

Dr. Sumera Qazi

Morphology of Benign Proliferative Breast Lesions in the Mestectomy Specimens.

· Awarded Degree

Dr. Fatima Rashid

Morphological Study of Renal Lesions in Systemic Lupus Erythematosis

· Awarded Degree

Session 2010 – 2012

Dr. Ehsan Ullah

Correlation of Mast Cell and Microvascular Density in Carcinoma of Lung

· Awarded Degree

Dr. Raees Abbas

Smoking Related Interstitial Fibrosis and Interstitial Lung Disease: An Autopsy Study

· Awarded Degree

Dr. Saadia Raza

Morphological changes in liver and kidney of rodents induced by indigenous preparation of gold

· Awarded Degree

Dr. Sakina Jamil

Mercury Kushta induced morphological changes in liver and kidney of rats

· Awarded Degree

Session 2011 -13

Dr. Farwa Batool

Clininopathological Pattern and Classification of Breast Carcinoma based on ER/PR and HER2/ neu Immunohistochemistry

· Awarded Degree

Dr. Nasim Aslam

Effects of Cadmium Salt on Kidney Tissue of White Rats

· Awarded Degree

Session 2012 – 2014

Dr. M. Zain Mehdi

Expression of minichromosome maintenance 2 and Ki-67 as proliferation markers in Renal cell carcinoma

· Awarded Degree

Dr. Hira Kareem

Effects of Copper Preparations on Kidneys of Albino Rats

· Awarded Degree

Dr. Nushmia Baig

Expression of TAMS and M2 Macrophages in Different Histological Grades of Breast Carcinoma

· Awarded Degree

Dr. Irfan Basheer

Expression of Isocitrate Dehydrogenase I and internexin alpha in gliomas

· Awarded Degree

Session 2013 – 2015

Dr. Sobia Khalid

Expression of NGAL in Class I-V Lupus Nephritis Using Immunohistochemical and Immunofluorescent Techniques

· Awarded Degree

Dr. Sadaf Shafique

Effects of Arsenic Preparations on Kidney and Testes of Wister Rats

· Awarded Degree

Dr. Qurat Ul Ain

Expression of Ki-67 & P53 as a Prognostic Marker in Wilms’ Tumour

· Awarded Degree

Dr. Hadia Rafique

Detection of DNA Mismatch Repair Antibodies AMS2 MSH6 MSH2 MLH1 in Carcinoma of Breast

· Awarded Degree

Session 2014-16

Dr. Rizwan Rasul

Lead Kushta Induced Morphological Changes in Kidney of Rats

· M.Phil. part 1 exam clearance pending

Session 2015-17

Dr. Ayesha Suleman

Immunohistochemistry of H. pylori, characterization of its different serological strains and histological grading of chronic gastritis

· Awarded Degree

Dr. Azka Iqbal

Immunohistochemical Expression of Interleukin-30 in Prostate Cancer

· Thesis submitted

Dr. Wajeeha Arooj

Detection of Mycobacterium Tuberculosis in Patients with Lymph Node TB by Immunohistochemistry and Indirect Immunofluorescence Techniques

· Research in Progress

Iqra Ijaz

Detection of Mycobacterium Tuberculosis through Immunocytochemistry & Immunofluorescence from Cervical Lymph node Aspirates

· M.Phil. Cytotechnology

· Thesis submitted

Mr. Ghulam Rasool

Detection of H. Pylori and MLH1 Gene Expression Analysis by Polymerase Chain Reaction in Patients of Chronic Gastritis with and without H.Pylori

· Awarded Degree

Dr. Raza Abbas

Detection of Mycobacterium Tuberculosis in Formalin Fixed Parrafin Embedded Tissues through Ziehl-Neelsen Stain and PCR

· Awarded Degree

Dr. Mishal Sikandar

Hirschsprung’s Disease and the Role of Calretinin in Rectal Biopsies

· Awarded Degree

Dr. M Rashid

Protective Effect of Ginger on alcohol Induced Steatotic Liver of Rats

· Awarded Degree

Asia Rao

Detection of Helicobacter Pylori through Histochemistry and Immunofluorescent Staining in Biopsies of Patients with Chronic Gastritis

· Awarded Degree

Ayesha Saeed

Comparative determination of integrity of RNA in experimental tissues fixed in formalin, universal molecular fixative and honey

· Project taken over by department

Dr. Iram Asrar

11. Immunohistochemical Expression and Association of Gata3 with ER Status and Nottingham Grading System of Breast Carcinoma

· Awarded Degree

Dr. Waqas Arshad Mughal

Immunohistochemically Expression of Secreted Protein Acidic and Rich in Cysteine (SPARC) in Biopsies of Patients with Primary Breast Carcinoma of Different Histologic Grades and Clinical Stages

· Thesis work completed

Ahsan Iqbal

“Diagnostic Utility of Manual Liquid-based Cytology (MLBC) and Cell Block Preparation in Fine Needle Aspiration Cytology (FNAC) Specimens”

· Writing Synopsis

Nida Ali Ahmed

Comparative Determination of Integrity of DNA in Experimental Tissues Fixed in Formalin, Universal molecular Fixative and Honey

· Thesis writing in progress)

Session 2016-18

Dr. Sobia Idrak

Classification of cervical cytological lesions in HIV positive patients according to Bethesda system 2014

· Thesis work completed

Session 2017-19

Dr. Kainat Farrukh

Cervical Cytological Changes in Relation with herpes Simplex Virus 1&2 in Pregnant Females of Local Population

· Thesis Submitted

Dr. Muntaha Masood

Expression of Isocitrate Dehydraogenase-! In Gliomas Presenting in Local Population

· Thesis Submitted

Dr. Maham Javed

Cytological Changes in Relation with Human Papilloma in Patients with Oral Potentially Malignant Lisions

· Thesis Submitted

Mr. Tuaha Amjad

Comparative antigenic determination on frozen section by Michel’s Transport medium and direct freezing methods

· Synopsis Approved

Session 2018-20

Miss Sumaira Niaz

Cytokeratin 5 Expression on Immunohistochemistry by using Cell Block and Immnocytochemistry by using Liquid Based Cytology

· Thesis writing in progress

Session 2019-21

Dr. Shameen Fatima Shoaib

Nill

First Year in Progress

Miss. Gulfishan Zameer

Nill

First Year in Progress

Dr. Humaira Javed

Nill

First Year in Progress

YEAR WISE ENROLLMENT OF Ph.D STUDENTS

Year

Students’ Name

Research Title

Status

2004

Dr. Samina Khokher

Prediction of Efficacy of Chemotherapy in Breast Cancer-Development of Efficacy Index

· Degree Awarded

2006

Dr. Waseem Haider

Characterisation of Y-STR in Sexual Assault Victims and Collection of Allele Frequencies and Haplotypes in Punjab

· Degree Awarded in 2008

2010

Dr. Nadeem Afzal

The Role of Genetics and Immune Mechanisms in the Pathogenesis of Diabetic Retinopathy

· Degree Awarded

2010

Dr. Abdul Mannan Babar

Surgical Adjuvant Intralesional Cytokines Versus Steriods Hypertrophic Scars and Keloids

· Degree Awarded

2011

Dr. Azhar Qayyum

Kras Oncogenic Mutation Pattern in Pakistani Patients Presenting with Colorectal Carcinoma in a Northern Tertiary Referral Centre

· Degree Awarded in 2016

2012

Dr. Nadia Naseem

Immunohistochemical and Genetic characterization of Muscular Dystrophies in Local Population

· Degree Awarded in 2016

2013-16

Dr. Usman Shams

Role of Epigenetic Regulator EZH2 in Tumorogenesis of Skin

· Synopsis approved by ASRB in 2016 under supervision of Prof. AH Nagi and Co-supervision of Dr Saqib Mehmood

· Practical Work in progress

· Histopathology component is completed while 20% of molecular component of research is to yet to be carried out.

Dr. Nausheen Henna

Morphological Pattern of Hepatitis B Virus Associated Nephropathy and its Association with Hepatitis B Virus Genotypes

· Synopsis approved by ASRB in 2016 under supervision of Prof. AH Nagi and Co-supervision of Dr Saqib Mehmood

· Practical Work in progress

· Histopathology component is completed while 20% of molecular component of research is to yet to be carried out.

2014-17

Dr. Raees Abbas

Expression and Sequencing Analysis of GATA3 gene in local Breast Cancer Population

· Working on Research Topic since 2015.

· Student was called and emailed to submit draft of synopsis in 2017, 2018, 2019, 2020. However, he hasn’t reported to department about his progress yet.

Dr. Farha Bano Niazi

Correlation of STIC Positivity in Fallopian Tube with Serous Carcinoma of Ovary and its Relation with BRCA 1 Mutations

· Synopsis approved by ASRB in 2017 under supervision of Prof. AH Nagi and Co-supervision of Dr Shah Jahan

· Student’s funds will be covered partially by HEC approved project.

· Histology and partial molecular components are completed in Histopathology lab and Cell Biology Lab

· WB in progress in Cell Biology lab.

2015-18

Dr. Atika Masood

Mutations in cancer susceptibility genes and expression of poly ADP-ribose protein in relation to chemotherapy response in patients with surface epithelial ovarian carcinoma

· Comprehensive examination passed in 2017.

· Synopsis approved by ASRB in 2020 under supervision of Prof Nadia Naseem

· Practical work in process

Dr. Rahat Sarfraz

Analysis of copy number variants and their protein expression in response to treatment in surface epithelial ovarian cancer patients”

· Comprehensive examination passed in 2017.

· Synopsis approved by ASRB in 2020 under supervision of Prof Nadia Naseem

· Practical work in process

Dr. Mahvish Hussain

· Passed PhD Comprehensive Examination in 2017.

· Synopsis writing in progress

2016-19

Dr. Seema Butt

· Comprehensive examination failed in 2019. Second attempt awaited.

Dr. Bushra Nisar

Classification of cervical cytological changes with serological and molecular characterization of sexually transmitted viral infection in females of local population”

· Comprehensive examination passed in 2019.

· Synopsis approved by ASRB in 2020 under supervision of Prof Nadia Naseem

· Practical work in process

Co-Supervision (Different Departments):

2014-17

Dr. Kashif Azam

(Ph.D oral Pathology)

“Identification and characterization of cancer stem cells in head and neck squamous cell carcinoma with and without human papilloma virus”

· Synopsis Approved by ASRB under supervision of Prof Nadeem Afzal and Co-supervision of Prof AH Nagi and Dr Shah Jahan.

· Student’s funds will be covered partially by HEC approved project.

· Sampling & Procurement in Process

· Practical work of histology is ongoing in Histopathology lab.

2015-18

Dr. Nauman Rauf Khan

mi RNA differential expression analysis in blood plasma of head and necks squamous cell carcinoma patients before and after surgical therapy and HNSCC tissue section with healthy tissue counterpart

· Passed PhD Comprehensive Examination in 2017.

· Synopsis approved in 2018

· Thesis work in progress

2018-2021

Mr. Ateeq Ashraf

Expressional profiling, sequencing analysis and in vitro investigations of CXC chemokine receptors in breast cancer

· Passed PhD Comprehensive Examination in 2019.

· Synopsis approved in 2020.

· Thesis work in progress