UHS-Dept

Research Publications of Pharmacology

2021

IF

1

Hafsa Izhar, Arham Shabbir, Muhammad Shahzad. Phyllanthus reticulatus Prevents Ethanol-Induced Gastric Ulcer via Downregulation of IL-8 and TNF-? Levels. Evidence-Based Complementary and Alternative Medicine. Volume 2021, Article ID 1734752

1.81

2

Haseeb Ahsan, Hafiz Muhammad Irfan, Alamgeer, Muhammad Shahzad. Potential of ephedrine to suppress the gene expression of TNF-?, IL-1?, IL-6 and PGE2: A novel approach towards management of rheumatoid arthritis. Life Sciences282(2021). 29(3):673-682

4.473

3

Basma Ijaz, Arham Shabbir, Muhammad Shahzad. Amelioration of airway inflammation and pulmonary edema by Teucrium stocksianum via attenuation of pro-inflammatory cytokines and up-regulation of AQP1 and AQP5. Respiratory Physiology & Neurobiology 284 (2021) 103569

1.931

4

Amin A., Sheikh N., Mukhtar M., Saleem T., Akhtar T., Fatima N., Mehmood R. 2021. Association of Interleukin-17 Gene Polymorphisms with the Onset of Rheumatoid Arthritis. Immunobiology. 226(1): 152045

3.144

5

Haseeb Ahsan, Hafiz Muhammad Irfan, Alamgeer, Muhammad Shahzad. Anti?rheumatic activity of pseudoephedrine (a substituted phenethylamine) in complete Freund’s adjuvant?induced arthritic rats by down regulating IL?1?, IL?6 and TNF?? as well as upregulating IL-4 and IL-10. Inflammopharmacology. https://doi.org/10.1007/s10787-021-00804-z March, 2021.

3.023

6

Cathrine Axfors et al. (2021). Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials. NATURE COMMUNICATIONS. 12:2349 | https://doi.org/10.1038/s41467-021-22446-z

12.12

7

Muhammad Shoaib Zafar, Muhammad Shahzad, Ali Rafi, Glenda Gobe, and David Vesey. "Salicylaldehyde and benzaldehyde derivatives of pregabalin and their metal complexes (copper and zinc) ameliorates airway inflammation." In BRITISH JOURNAL OF PHARMACOLOGY, vol. 178, no. 2, pp. 484-485. 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY, 2021

8.739

8

Fatima, N., Sheikh, N., Satoskar, A.R., Akhtar, T., Tayyeb, A. Ashfaq, I., Rayan, N., Ambreen, S., Jha, B.K. and Oghumu, S. 2021. Effect of Short-Term Tacrolimus Exposure on Rat Liver: An Insight into Serum Antioxidant Status, Liver Lipid Peroxidation, and Inflammation. Mediators of Inflammation. 2021: 1-12

4.711

9

Asghar, A., Akhtar, T., Batool, T., Khawar, M.B., Nadeem, S., Mehmood, R. and Sheikh, N. 2021. High-fat diet-induced splenic, hepatic, and skeletal muscle architecture damage: cellular and molecular players. Molecular and Cellular Biochemistry. 2021:1-13

3.396

10

Fatima, N., Sheikh, N., Satoskar, A.R., Jha, B.K., Akhtar, T., Tayyeb, A. and Ashfaq, I. 2021. Interaction of tacrolimus through hedgehog signaling pathway: An in vitro evaluation using rat hepatocytes. Human and experimental toxicology. 40 (3):138-147

2.903

11

Rehman, A., Akhtar, T., Hameed, N. and Sheikh, N. 2020. In vivo assessment of bisphenol A induced histopathological alterations and inflammatory gene expression in lungs of male wistar rats. Human and experimental toxicology. 40 (3):538-549

2.903

12

Maryam Bi Bi,Aatika Sadia, Muhammad Shahzad. Efficacy of Investigative Candidate Drugs Against SARS CoV-2: An update on pre-clinical and clinical trials. Thai Journal of Pharmaceutical Sciences ( TJPS-2021-0055.R1)

Y

13

Analyses of ABO blood groups with susceptibility and symptomatic variations of COVID-19 infection, a questionnaire-based survey Asma Komal, Mamoona Noreen, Junaid Akhtar, Muhammad Imran, Muhsin Jamal, Muhammad Atif, Juma Khan, Muhammad Roman, Faiz Ul Haq, Usman Aftab, Abdul Ghaffar, Yasir Waheed first published: 02 August 2021 https://doi.org/10.1111/apm.13169, Acta Pathologica, Microbiologica, et Immunologica Scandinavica pp 1-8

3.205

2020

14

Rabiya Naz, Zaheer Ahmad, Muhammad Shahzad. Amelioration of rheumatoid arthritis by Anacardium occidentale via inhibition of collagenase and lysosomal enzymes. Evidence-Based Complementary and Alternative Medicine. Volume 2020, Article ID 8869484.

1.81

15

Aisha Mobashar, Arham Shabbir, Muhammad Shahzad. Evaluation of immunomodulatory and anti-arthritic potential of Trigonella gharuensis extracts. Evidence-Based Complementary and Alternative Medicine. Evid Based Complement Alternat Med. 2020 Dec 12;2020:8836080.

1.81

16

Javed Akram, Shehnoor Azhar, Muhammad Shahzad. Pakistan Randomized and Observational Trial to Evaluate Coronavirus Treatment (PROTECT) of Hydroxychloroquine, Oseltamivir and Azithromycin to treat newly diagnosed patients with COVID-19 infection who have no comorbidities like diabetes mellitus: A structured summary of a study protocol for a randomized controlled trial.. Trials (2020) 21:702 https://doi.org/10.1186/s13063-020-04616-4

1.883

17

Muhammad Shoaib Zafar and Muhammad Shahzad. "Immunomodulatory effect of pregabalin derivatives and their metal complexes on ovalbumin-induced acute lung remodelling." In British Journal of Pharmacology, vol. 177, no. 11, pp. 2624-2624. 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY, 2020.

8.739

18

1. Sumera Qasim, Alamgeer, Saima Kalsoom, Muhammad Shehzad, Hafiz Muhammad Irfan, Muhammad Shoaib Zafar, Ishfaq Ali Bukhari, Fahim Vohra and Sibtain Afzal, 2020. Appraisal of disease-modifying potential of amlodipine as an anti-arthritic agent: new indication for an old drug. Inflammopharmacology, pp.1-16. (Impact Factor=4.473)

3.023

19

Ammara Saleem , Mohammad Saleem , Muhammad Furqan Akhtar , Muhammad Shahzad. Polystichum braunii extracts inhibit Complete Freund's adjuvant-induced arthritis via upregulation of I-?B, IL-4, and IL-10, downregulation of COX-2, PGE2, IL-1?, IL-6, NF-?B, and TNF-?, and subsiding oxidative stress. Inflammopharmacology . 2020. Dec;28(6):1633-1648

3.023

20

Sumera Qasim , Alamgeer , Saima Kalsoom, Muhammad Shahzad. Appraisal of disease-modifying potential of amlodipine as an anti-arthritic agent: new indication for an old drug. Inflammopharmacology . 2020 Aug;28(4):1121-1136

3.023

21

Ammara Salem, Mohammad Saleem, Muhammad Furqan Akhtar, Muhammad Shahzad, Shah Jahan. 2020. Moringa rivae leaf extracts attenuate Complete Freund’s adjuvant-induced arthritis in Wistar rats via modulation of inflammatory and oxidative stress biomarkers. Inflammopharmacology. 2020 Feb;28(1):139-151. doi: 10.1007/s10787-019-00596-3.

3.023

22

Hameed N., Abbasi, M.H., Akhtar T. and Sheikh, N. 2020. Hematotoxicity and testicular injury induced by Bisphenol A in Rattus norvegicus. J Biol Regul Homeost Agents. 34(4): 1493-1500

1.506

23

Basit F., Akhtar T., Hameed N., Abbasi M.H. and Sheikh N. 2020. Subchronic toxicity of Bisphenol A on the architecture of spleen and hepatic traces metal levels and protein profile of adult male wistar rats. Human and experimental toxicology. 39(10): 1355-1363

2.903

24

Ghafoor, S., Akhtar T., Batool T., Khawar M.B. and Sheikh N. 2020. Alterations in hepatic trace elements and ferritin expression in high energy diet fed rat model. J Biol Regul Homeost Agents. 34(3): 1229-1233

1.506

25

Akhtar T., Ali, G. and Sheikh N. 2020. Immunosupppressant induced oxidative stress and iron: A paradigm shift from systemic to intrahepatic abnormalities. Oxidative Medicine and Cellular Longevity.2020:1-10

6.543

26

Jawad Rasheed, Akhtar Jamil, Alaa Ali Hameed, Usman Aftab, Javaria Aftab, Syed Attique Shah, Dirk Draheim., 2020. A survey on artificial intelligence approaches in supporting frontline workers and decision makers for COVID-19 pandemic. Chaos, Solitons & Fractals, p.110337.

5.944

27

Usman Aftab, Ali Rafi, Muhammad Shahzad, 2020, COVID-19 Outbreak: Spread, Symptoms, Treatment and Research, LETTER TO THE EDITOR Biomedica. 2020; 36(COVID19-S2): 53-5

PMDC

2019

28

Abdullah Abdo, Muhammad Shahzad*, Muhammad Ikram Ullah , Saqib Mehmood. Genetic association of insulin receptor substrate-1 (IRS-1, rs1801278) gene with insulin resistant of type 2 diabetes mellitus in a Pakistani population. Mol Biol Rep . 2019 Dec;46(6):6065-6070. doi: 10.1007/s11033-019-05041-w

1.402

30

Hira Shahid, Muhammad Shahzad*, Arham Shabbir, Gulpash Saghir. Immunomodulatory and Anti-Inflammatory Potential of Curcumin for the Treatment of Allergic Asthma: Effects on Expression Levels of Pro-inflammatory Cytokines and Aquaporins. Inflammation (2019) DOI: 10.1007/s10753-019-01066-2

3.923

31

Abdullah Abdo Albegali, Muhammad Shahzad*, Muhammad Ikram Ullah, Saqib Mahmood, Maryam Rashid. Association of genetic polymorphism of PC-1 gene (rs1044498 Lys121Gln) with insulin resistant type 2 diabetes mellitus in Punjabi Population of Pakistan. Mol Genet Genomic Med. 2019 Aug;7(8):e775. doi: 10.1002/mgg3.775. Epub 2019 Jun 28.

2.183

32

Adnan Jehangir, Muhammad Shahzad*, Khadija, Akbar Waheed. Zinc and Iron Complexes of Oleanolic Acid, (Oa) Attenuate Allergic Airway Inflammation in Rats. Inflammopharmacology. 2019 May 8. doi: 10.1007/s10787-019-00597-2.

3.023

33

FatimaAhsan, ArhamShabbir, MuhammadShahzad, AishaMobashar. Amelioration of allergic asthma by Ziziphora clinopodioides via upregulation of aquaporins and downregulation of IL4 and IL5. Respiratory Physiology & Neurobiology Volume 266, August 2019.

1.931

34

Umme Habiba Hassan, Alamgeer, Muhammad Shahzad. Amelioration of adjuvant induced arthritis in Sprague Dawley rats through modulation of inflammatory mediators by Ribes alpestre Decne. Journal of Ethnopharmacology 235 (2019) 460–471.

3.69

35

Ambreen Malik Uttra, Alamgeer, Muhammad Shahzad. Ribes orientale: A novel therapeutic approach targeting rheumatoid arthritis with reference to pro-inflammatory cytokines, inflammatory enzymes and anti-inflammatory cytokines. Journal of Ethnopharmacology 237 (2019) 92–107.

3.69

36

Characteristics with Bone Mineral Density in Pakistani Females. Saba Tariq, Mukhtiar Baig, Sundus Tariq. Muhammad Shahzad4Status of bone health and association of socio-demographic. Pak J Med Sci May - June 2019 Vol. 35 No. 3

0.754

37

Sabeen Arjumand, Muhammad Shahzad*, Arham Shabbir, Muhammad Zubair Yousaf. Thymoquinone attenuates rheumatoid arthritis by downregulating TLR2, TLR4, TNF-?, IL-1, and NF?B expression levels. Biomedicine & Pharmacotherapy 111 (2019) 958–963

4.545

38

Maryam Rashid, Muhammad Shahzad*, Saqib Mahmood, Khurshid Khan. Variability in the therapeutic response of Metformin treatment in patients with type 2 diabetes mellitus. Pak J Med Sci January - February 2019 Vol. 35 No. 1

0.754

39

Umme Habiba Hasan, Alamgeer, Muhammad Shahzad, Shah Jahan. Inhibitory effects of Clematis orientalis aqueous ethanol extract and fractions on inflammatory markers in complete Freund’s adjuvant?induced arthritis in Sprague–Dawley rats. Inflammopharmacology Aug;27(4):781-797.

3.023

40

Siddiqui Sara, Ashraf Komal, Malka M Samra, Muhammad Shahzad. Immunological and clinical evaluation of Triticum aestivum aeroallergens in asthmatic patients. SPG BioMed 2019

41

Ambreen S., Akhtar T., Hameed, N., Ashfaq, I. and Sheikh N. 2019. In-vivo evaluation of histopathological alterations and trace metals estimation of small intestine in bisphenol A intoxicated rats. Canadian journal of Gastroenterology and Hepatology, 2019:1-8.

2.055

42

Batool T., Akhtar T. Asghar A., Khawar M.B. and Sheikh N. 2019. Analysis of changes in hepatic expression and tissue architecture of heart and kidney in association with diet-induced obesity in Rattus norvegicus. J Biol Regul Homeost Agents, 33(1):221-224

1.469

43

Maryam Munawar, Shoaib Asif, Haroon Habib, Muhammad Shoaib Zafar and Muhammad Waqas, 2019. Outlook on Anti-Hyperlipidemic Outcome of Moringa Oleifera in Relationship with Statins. International Journal of Biology, Pharmacy and Allied Sciences, 8 (6):1165-1176.

44

Adeela Fatima, Usman Aftab, Khaled A. Shaaban, Jon S. Thorson and Imran Sajid, 2019, BMC Microbiology, Spore forming Actinobacterial diversity of Cholistan Desert Pakistan: Polyphasic taxonomy, antimicrobial potential and chemical profiling, 19:49 https://doi.org/10.1186/s12866-019-1414-x

2.82