Research and Publications

Research Projects

• Pakistan “Randomized and Observational Trial to Evaluate Coronavirus Treatment (PROTECT) of Hydroxychloroquine, Oseltamivir and Azithromycin” 2022. (Completed)
• Role of Indoleamine 2,3-dioxygenase (IDO) in Glucocorticoid-Resistant Asthma Patients and Effect of Thiazolyl and Thaizolidinonyl Tetrahydronapthalene Derivatives through Modulation of IDO Activity on Acute Lung Remodelling (Pakistan Science Foundation). PSF (1.9 Million), 2023 (Continued)
• Role of Indolamine 2,3 Dioxyenase (IDO) in glucocorticoid-resistant asthma patients and effect of synthetic & natural compounds through modulation of IDO in acute lung remodeling, NRPU 2018-19 (1.8 Million) 2024 (Completed)
• Alternative therapeutic approaches: hepatoprotective potential of quercetin against experimentally induced liver fibrosis. HEC SRGP 2020 (Completed)
• Activity of indigenous Actinomycetes extracts against different cancer cell lines. HEC SRGP, 2018-19 (0.5 Million) (Completed)
• Analysis of Acinetobacter baumannii for drug resistance, virulence features and alternative treatment options. HEC, 2018-20 (Completed)
• Anti-Inflammatory Effect of Zingiber Officinale (Ginger) and Methylprednisolone on the mice Model of Allergic Airway Inflammation funded by Pakistan Science Foundation in 2010 (Completed)
• Optimization of mtDNA Amplification system for Forensic Application funded by HEC Pakistan in 2012 (Completed)

Last 5 Years List of Publications

• Kaikai Lu et al. PDCD4 Deficiency in Hepatocytes Exacerbates Nonalcoholic Steatohepatitis Through Enhanced MHC Class II Transactivator Expression. Metabolism., December 2024, 156036. DOI: 10.1016/j.metabol.2024.156036 Impact Factor: 9.8
• Kaikai Lu, Yimeng Zhou, Lei He, Ya Li, Muhammad Shahzad, Dongmin Li. Coprococcus protects against high-fat diet-induced nonalcoholic fatty liver disease in mice. Journal of Applied Microbiology. 2024 Jun 3;135(6). DOI: 10.1093/jambio/lxae125 Impact Factor: 4.0
• Hafiz Muhammad Ishaq, Riffat Yasin, Imran Shair Mohammad, Yang Fan, Huan Li, Muhammad Shahzad, Jiru Xu. The Gut-Brain-Axis: A Positive Relationship between Gut Microbial Dysbiosis and Glioblastoma Brain Tumour. Heliyon 10 (2024) e30494. DOI: 10.1016/j.heliyon.2024.e30494 Impact Factor: 4.0
• Effectiveness of early pharmaceutical interventions in symptomatic COVID-19 patients: A randomized clinical trial. Pak J Med Sci May - June 2024. Vol. 40 No. 5. DOI: 10.12669/pjms.40.5.8757, Impact Factor: 2.339
• Ahmad I, Nadeem A, Mushtaq F, Zlatkov N, Shahzad M. Csu pili dependent biofilm formation and virulence of Acinetobacter baumannii. NPJ Biofilms Microbiomes. 2023 Dec 14;9(1):101. DOI: 10.1038/s41522-023-00465-6 Impact Factor: 9.20
• Kiran Mashaal; Arham Shabbir; Muhammad Shahzad; Aisha Mobashar. Amelioration of Rheumatoid Arthritis by Fragaria nubicola (Wild Strawberry) via Attenuation of Inflammatory Mediators in Sprague Dawley Rats. Medicina 2023, 59(11), 1917. DOI: 10.3390/medicina59111917 Impact Factor: 3.0
• Saba Tariq, Sundus Tariq, Shahad Abduljalil Abualhamael, Mukhtiar Baig, Ahmad Azam Malik, Muhammad Shahzad. Osteoprotegerin genetic polymorphisms and their influence on therapeutic response to ibandronate in postmenopausal osteoporotic females. PLOS ONE. 2023. DOI: 10.1371/journal.pone.0291959 Impact Factor: 3.752
• Sara Sattar, Arham Shabbir, Muhammad Shahzad, Tasleem Akhtar, Syed Muneeb Anjum, Mohammed Bourhia, Hiba-Allah Nafidi, Yousef A. Bin Jardan, Musaab Dauelbait and Aisha Mobashar. Evaluation of anti-inflammatory and immunomodulatory potential of Lawsone (2-hydroxy-1,4-naphthoquinone) using pre-clinical rodent model of rheumatoid arthritis. Frontiers in Pharmacology. DOI: 10.3389/fphar.2023.1279215 Impact Factor: 5.6
• Sara Sattar, Arham Shabbir, Muhammad Shahzad, Tasleem Akhtar, Arfan Ahmad, Sulaiman Mohammed Alnasser, Bushra Riaz, Shaik Karimullah and Ashfaq Ahmad Eichhornia crassipes Ameliorated Rheumatoid Arthritis by Modulating Inflammatory Cytokines and Metalloproteinase Enzymes in a Rat Model. Medicina 2023, 59, 1594. DOI: 10.3390/medicina59091594 Impact Factor: 3.0
• Tasleem Akhtar, Nadia Naseem, Usman Aftab, Muhammad Shoaib Zafar, Safdar Hussain, Muhammad Shahzad, Glenda Carolyn Gobe. Chrysin Is Immunomodulatory and Anti-Inflammatory against Complete Freund’s Adjuvant-Induced Arthritis in a Pre-Clinical Rodent Model. Pharmaceutics. 2023 Apr 12;15(4):1225. DOI: 10.3390/pharmaceutics15041225 Impact Factor: 6.525
• Kiran Mashaal, Arham Shabbir, Mahtab Ahmad Khan, Huma Hameed, Muhammad Shahzad. Anti-Arthritic and Immunomodulatory Potential of Methanolic, n-Hexane, and Ethyl Acetate Fractions of Bark of Acacia modesta on Complete Freund’s Adjuvant-Induced Arthritis in Rats. Pharmaceutics 2023, 15(9)2228. DOI: 10.3390/pharmaceutics15092228 Impact Factor: 6.525
• Tasleem Akhtar, Nadia Naseem, Usman Aftab, Safdar Hussain, Muhammad Shahzad. Evaluation of therapeutic potential of ivermectin against complete Freund’s adjuvant-induced arthritis in rats: Involvement of inflammatory mediators. Fundamental & Clinical Pharmacology. 2023 Apr 21. DOI: 10.1111/fcp.12902 Impact Factor: 2.74
• Tasleem Akhtar, Arham Shabbir, Usman Aftab, Muhammad Shahzad. Sitagliptin ameliorates diabetic nephropathy by upregulating renal nephrin and podocin expression through modulation of adipokines levels. Fundam & Clin Pharmacol. 2023 Jan. DOI: 10.1111/fcp.12864 Impact Factor: 2.74
• Faiza Ali, Zeb Saddiqe, Muhammad Shahzad, Ali Rafi, Madeeha Javed, Faiz-ul Haq, Sidrah Saleem, Shabana Kusara. Crotalaria medicaginea Lamk.: An unexplored source of anticancer, antimicrobial and antioxidant agents. European Journal of Integrative Medicine. Volume 58, February 2023, 102226. DOI: 10.1016/j.eujim.2023.102226 Impact Factor: 1.813
• Mubeen Fatima, Momal Babar, Muhammad Shoaib Zafar (Book Chapter) Curcumin: A Potential Therapeutic Agent for Human Health and Diseases -- Current Status and Future Perspectives. In book: IGI-Global: Pharmacological Benefits of Natural Agents. Feb 2023. DOI: 10.4018/978-1-6684-6737-4.ch012 Impact Factor: N/A (Book Chapter)
• Maham Israr, Nadia Naseem, Tasleem Akhtar, Usman Aftab, Muhammad Shoaib Zafar, Muhammad Asif Faheem, Muhammad Shahzad. Nimbolide attenuates complete Freund’s adjuvant induced arthritis through expression regulation of toll‐like receptors signaling pathway. Phytother Res, 2022 Nov 27. Online ahead of print [Impact Factor 6.388]
• Nadeem Sheikh, Shakira Shakeel, Tasleem Akhtar, Muhammad Babar Khawar, Inimical impact of high-fat diet on expression of heme oxygenase-1, trace metals content, and associated intestinal histopathology, Toxicology Research, 2022 Dec 15. Online ahead of print [Impact Factor 2.680]
• Umaira Ahsan, Fizza Mushtaq, Sidrah Saleem, Abdul Malik, Hira Sarfaraz, Muhammad Shahzad, Bernt Eric Uhlin and Irfan Ahmad. Emergence of high colistin resistance in carbapenem-resistant Acinetobacter baumannii in Pakistan and its potential management through immunomodulatory effect of an extract from Saussurea lappa. Frontiers in Pharmacology. 2022. Ahead of publication [Impact Factor 5.988]
• Bushra Shaukat, Malik Hassan Mehmood, Babar Murtaza, Farah Javaid, Muhammad Tariq Khan, Maryam Farrukh, Reemal Rana, Muhammad Shahzad. Ajuga bracteosa Exerts Antihypertensive Activity in l-NAME-Induced Hypertension Possibly through Modulation of Oxidative Stress, Proinflammatory Cytokines, and the Nitric Oxide/Cyclic Guanosine Monophosphate Pathway. ACS Omega. 2022 Sep 8;7(37):33307-33319 [Impact Factor 4.132]
• Zari Salahuddin, Ali Rafi, Hafsa Muhammad, Usman Aftab, Tasleem Akhtar, Muhammad Shoaib Zafar and Muhammad Shahzad. Revolutionalizing the age old conventional treatment of psoriasis: An animal based comparative study between methylprednisolone and different doses of a novel anti-oxidant humanin analogue (HNG). International Immunopharmacology. June 22, 110(2022) 108990. [Impact Factor 5.714]
• Andleeb Aslam, Nadeem Sheikh, Muhammad Shahzad, Ghazala Saeed, Naz Fatima, Tasleem Akhtar. Quercetin ameliorates thioacetamide‐induced hepatic fibrosis and oxidative stress by antagonizing the Hedgehog signaling pathway. Journal of Cellular Biochemistry. 2022 Jun 13. doi: 10.1002/jcb.30296. Online ahead of print. [Impact Factor 4.480]
• Afshan Syed Abbas, Tasleem Akhtar, Najma Shaheen, Sumaira Aslam, Nadeem Sheikh. Mechanistic study of regulation of iron homeostasis by N. sativa seeds and P. ovata husks on high fat/high sucrose diet induced non-alcoholic fatty liver disease. Mol Biol Rep. 2022. 49(8):7417-7424 doi: 10.1007/s11033-022-07538-3 [Impact Factor 2.742]
• Shehnoor Azhar, Javed Akram, Muhammad Shahzad, Waqas Latif, Khalid Saeed Khan. Protocol of Pakistan randomized and observational trial to evaluate coronavirus treatment among newly diagnosed patients with COVID-19: Azithromycin, Oseltamivir, and Hydroxychloquine. Pak j Med Sci.2022. 38(5):1401-1408. [Impact Factor 2.339]
• Shafaq, Tasleem Akhtar, Hafiz Muhammad Ishaq, Muhammad Shahzad. Pharmacological effects of Artocarpus lakoocha methanol extract on inhibition of squalene synthase and other downstream enzymes of the cholesterol synthesis pathway. Pharm Biol. 2022 Dec;60(1):840-845. [Impact Factor 3.889]
• Sabeen Irshad, Arham Shabbir, Hina Aslam, Tasleem Akhtar, Muhammad Shahzad. Carica papaya ameliorates thrombocytopenia through upregulation of Interleukin-11 and modulation of thrombopoietin in mouse model of carboplatin-induced myelosuppression. Mol Biol Rep 2022 Jun;49(6):4633-4641. [Impact Factor 2.742]
• Aisha Mobashar, Arham Shabbir, Muhammad Shahzad, Glenda Gobe. Preclinical Rodent Models of Arthritis and Acute Inflammation Indicate Immunomodulatory and Anti-Inflammatory Properties of Juglans regia Extracts. Evid Based Complement Alternat Med 2022 Apr 5;2022:1695701. [Impact Factor 2.650]
• Shanila Akhter, Hafiz Muhammad Irfan, Alamgeer, Shah Jahan, Muhammad Shahzad, Muhammad Bilal Latif. Nerolidol: a potential approach in rheumatoid arthritis through reduction of TNF-α, IL-1β, IL-6, NF-kB, COX-2 and antioxidant effect in CFA-induced arthritic model. Inflammopharmacology, 2022 Apr;30(2):537-548. [Impact Factor 5.093]
• Muhammad Shahzad, Huan Chen, Tasleem Akhtar, Ali Rafi, Muhammad Shoaib Zafar, Yong-Tang Zheng. Human Immunodeficiency Virus: The potential of medicinal plants as anti‐retroviral therapy. J Med Virol 2022 Jun;94(6):2669-2674. [Impact Factor 20.693]
• Faiz Ul Haq, Muhammad Imran, Sidrah Saleem, Usman Aftab, Ayesha Ghazal, Investigation of Morchella esculenta and Morchella conica for their antibacterial potential against methicillin‐susceptible Staphylococcus aureus, methicillin‐resistant Staphylococcus aureus and Streptococcus pyogenes. Archives of Microbiology, (2022) 204:391 [Impact Factor 2.5]
• Faiz Ul Haq, Muhammad Imran, Sidrah Saleem, Ali Rafi and Jamal M Investigation of Three Morchella Species for Anticancer Activity Against Colon Cancer Cell Lines by UPLC-MS-Based Chemical Analysis. Appl Biochem Biotechnol. 2022 Sep 12. doi: 10.1007/s12010-022-04131-z. Epub ahead of print. PMID: 36094647. [Impact Factor 3.094]
• Muhammad Shoaib Zafar, Khadija Shahid, Glenda Gobe, Riffat Yasmin, Nadia Naseem and Muhammad Shahzad. Suppression of cytokine storm and associated inflammatory mediators by salicylaldehyde derivative of pregabalin: An innovative perspective for alleviating airway inflammation and lung remodeling. Volume 34, Issue 3, April 2022, 101877. [Impact Factor 3.829]
• Saba Tariq, Sundus Tariq, Shahad Abduljaleel, Muhammad Shahzad. Effect of Ibandronate Therapy on Serum Chemerin, Vaspin, Omentin-1 and Osteoprotegerin (OPG) in Postmenopausal Osteoporotic Females. Front. Pharmacol., 09 February 2022 | https://doi.org/10.3389/fphar.2022.822671, [Impact Factor 5.988]
• Yasmin, R., Zafar, M.S., Tahir, I.M., Asif, R., Asghar, S. and Raza, S.K., 2022. Biosorptive Potential of Pseudomonas species RY12 Toward Zinc Heavy Metal in Agriculture Soil Irrigated with Contaminated Waste Water. Dose-Response, 20(3), .15593258221117352. [Impact Factor 2.623]
• Naz Fatima, Nadeem Sheikh, Satoskar, A.R., Tasleem Akhtar, Asma Tayyeb, Isbah Ashfaq, Rayan, N., Saira Ambreen, Jha, B.K. and Oghumu, S. 2021. Effect of Short-Term Tacrolimus Exposure on Rat Liver: An Insight into Serum Antioxidant Status, Liver Lipid Peroxidation, and Inflammation. Mediators of Inflammation. 2021: 1-12. [Impact Factor 4.529]
• Hafsa Izhar, Arham Shabbir, Muhammad Shahzad, Aisha Mobashar, Syed Shoaib Ahmad. Phyllanthus reticulatus Prevents Ethanol-Induced Gastric Ulcer via Downregulation of IL-8 and TNF-α Levels. Evidence-Based Complementary and Alternative Medicine. Volume 2021, Article ID 1734752, [Impact Factor 2.650]
• Maryam Bi Bi, Aatika Sadia, Muhammad Shahzad. Efficacy of Investigative Candidate Drugs Against SARS CoV-2: An update on pre-clinical and clinical trials. Thai Journal of Pharmaceutical Sciences
• Ambreen Asghar, Tasleem Akhtar, Tayyaba Batool, Muhammad Babar Khawar, Sania Nadeem, Rabia Mehmood and Nadeem Sheikh. 2021. High-fat diet-induced splenic, hepatic, and skeletal muscle architecture damage: cellular and molecular players. Molecular and Cellular Biochemistry. 2021:1-13 [Impact Factor 3.842]
• Haseeb Ahsan, Hafiz Muhammad Irfan, Alamgeer, Muhammad Shahzad. Anti‐rheumatic activity of pseudoephedrine (a substituted phenethylamine) in complete Freund’s adjuvant‐induced arthritic rats by down regulating IL‐1β, IL‐6 and TNF‐α as well as upregulating IL‐4 and IL‐10. Inflammopharmacology. Jun;29(3):673-682 [Impact Factor 5.093]
• Fatima, N., Sheikh, N., Satoskar, A.R., Jha, B.K., Akhtar, T., Tayyeb, A. and Ashfaq, I. 2021. Interaction of tacrolimus through hedgehog signaling pathway: An in vitro evaluation using rat hepatocytes. Human and experimental toxicology. 40 (3):138-147. [Impact Factor 3.247]
• Asma Komal, Mamoona Noreen, Junaid Akhtar, Muhammad Imran, Muhsin Jamal, Muhammad Atif, Juma Khan, Muhammad Roman, Faiz Ul Haq, Usman Aftab, Abdul Ghaffar, Yasir Waheed. Analyses of ABO blood groups with susceptibility and symptomatic variations of COVID-19 infection, a questionnaire-based survey first published: 02 August 2021 https://doi.org/10.1111/apm.13169, Acta Pathologica, Microbiologica, et Immunologica Scandinavica pp 1-8 [Impact Factor 3.205]
• Saba Tariq, Sundus Tariq, Muhammad Shahzad. Association of serum chemerin with calcium, alkaline phosphatase and bone mineral density in postmenopausal females. Pak J Med Sci 2021 37(2):384-388 [Impact Factor 2.339]
• Rehman, A., Akhtar, T., Hameed, N. and Sheikh, N. 2020. In vivo assessment of bisphenol A induced histopathological alterations and inflammatory gene expression in lungs of male wistar rats. Human and experimental toxicology. 40 (3):538-549. [Impact Factor 2.339]
• Amin A., Sheikh N., Mukhtar M., Saleem T., Akhtar T., Fatima N., Mehmood R. 2021. Association of Interleukin-17 Gene Polymorphisms with the Onset of Rheumatoid Arthritis. Immunobiology. 226(1): 152045 [Impact Factor 3.152]
• Axfors et al. Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials. NATURE COMMUNICATIONS 2021 May 14;12(1):3001 [Impact Factor 12.121]
• Basma Ijaz, Arham Shabbir, Muhammad Shahzad. Amelioration of airway inflammation and pulmonary edema by Teucrium stocksianum via attenuation of pro-inflammatory cytokines and up-regulation of AQP1 and AQP5. Respiratory Physiology & Neurobiology 284 (2021) 103569 [Impact Factor 1.591]
• Rabiya Naz, Zaheer Ahmad, Muhammad Shahzad. Amelioration of rheumatoid arthritis by Anacardium occidentale via inhibition of collagenase and lysosomal enzymes. Evidence-Based Complementary and Alternative Medicine. Volume 2020, Article ID 8869484. [Impact Factor 1.813]
• Aisha Mobashar, Arham Shabbir, Muhammad Shahzad. Evaluation of immunomodulatory and anti-arthritic potential of Trigonella gharuensis extracts. Evidence-Based Complementary and Alternative Medicine. Evid Based Complement Alternat Med. 2020 Dec 12;2020:8836080. [Impact Factor 3.829]
• Hameed N., Abbasi, M.H., Akhtar T. and Sheikh, N. 2020. Hematotoxicity and testicular injury induced by Bisphenol A in Rattus norvegicus. J Biol Regul Homeost Agents. 34(4): 1493-1500. [Impact Factor 1.506]
• Javed Akram, Shehnoor Azhar, Muhammad Shahzad, Waqas Latif and Khalid Saeed Khan. Pakistan Randomized and Observational Trial to Evaluate Coronavirus Treatment (PROTECT) of Hydroxychloroquine, Oseltamivir and Azithromycin to treat newly diagnosed patients with COVID-19 infection who have no comorbidities like diabetes mellitus: A structured summary of a study protocol for a randomized controlled trial. Trials (2020) 21:702. [Impact Factor 1.883]
• Ammara Saleem, Mohammad Saleem, Muhammad Furqan Akhtar, Muhammad Shahzad. Polystichum braunii extracts inhibit Complete Freund’s adjuvant-induced arthritis via upregulation of I-κB, IL-4, and IL-10, downregulation of COX-2, PGE2, IL-1β, IL-6, NF-κB, and TNF-α, and subsiding oxidative stress. Inflammopharmacology. 2020 Dec;28(6):1633-1648 [Impact Factor 3.238]
• Basit F., Akhtar T., Hameed N., Abbasi M.H. and Sheikh N. 2020. Subchronic toxicity of Bisphenol A on the architecture of spleen and hepatic traces metal levels and protein profile of adult male wistar rats. Human and experimental toxicology. 39(10): 1355-1363 [Impact Factor 2.903]
• Jawad Rasheed, Akhtar Jamil, Alaa Ali Hameed, Usman Aftab, Javaria Aftab, Syed Attique Shah, Dirk Draheim. 2020. A survey on artificial intelligence approaches in supporting frontline workers and decision makers for COVID-19 pandemic. Chaos, Solitons & Fractals, p.110337. [Impact Factor 5.944]
• Ammara Salem, Mohammad Saleem, Muhammad Furqan Akhtar, Muhammad Shahzad, Shah Jahan. Moringa rivae leaf extracts attenuate Complete Freund’s adjuvant-induced arthritis in Wistar rats via modulation of inflammatory and oxidative stress biomarkers. Inflammopharmacology. 2020 Feb;28(1):139-151 [Impact Factor 3.238]
• Ghafoor, S., Akhtar T., Batool T., Khawar M.B. and Sheikh N. 2020. Alterations in hepatic trace elements and ferritin expression in high energy diet fed rat model. J Biol Regul Homeost Agents. 34(3): 1229-1233 [Impact Factor 1.506]
• Sumera Qasim, Alamgeer, Saima Kalsoom, Muhammad Shahzad, Irfan H.M., et al. Appraisal of disease-modifying potential of amlodipine as an anti-arthritic agent: new indication for an old drug. Inflammopharmacology. 2020 Aug;28(4):1121-1136 [Impact Factor 3.238]
• Akhtar T., Ali, G. and Sheikh N. 2020. Immunosupppressant induced oxidative stress and iron: A paradigm shift from systemic to intrahepatic abnormalities. Oxidative Medicine and Cellular Longevity. 2020:1-10 [Impact Factor 6.543]
• Usman Aftab, Ali Rafi, Muhammad Shahzad, 2020, COVID-19 Outbreak: Spread, Symptoms, Treatment and Research, LETTER TO THE EDITOR Biomedica. 2020; 36(COVID19-S2): 53-5 [HEC Y Category]
• Abdullah Abdo, Muhammad Shahzad, Muhammad Ikram Ullah, Saqib Mehmood. Genetic association of insulin receptor substrate-1 (IRS-1, rs1801278) gene with insulin resistant of type 2 diabetes mellitus in a Pakistani population. Mol Biol Rep. 2019 Dec;46(6):6065-6070. [Impact Factor 2.107]
• Naz, U., Sarwar, F., Sarwar, M.A., Ashraf, M.M., Zafar, M.S. and Khadam, M.W., 2019. Review of medical description of cervical cytology. Gomal Journal of Medical Sciences, 17(4), pp.150-154. [HEC Y Category]
• Munawar, M., Asif, S., Habib, H., Zafar, M.S. and Waqas, M., outlook on anti-hyperlipidemic outcome of moringa oleifera in relationship with statins. IJBPAS, June, 2019, 8(6): 1165-1176.
• Hira Shahid, Muhammad Shahzad, Arham Shabbir, Gulpash Saghir. Immunomodulatory and Anti-Inflammatory Potential of Curcumin for the Treatment of Allergic Asthma: Effects on Expression Levels of Pro-inflammatory Cytokines and Aquaporins. Inflammation 2019 Dec;42(6):2037-2047 [Impact Factor 2.939]
• Ambreen S., Akhtar T., Hameed, N., Ashfaq, I. and Sheikh N. 2019. In-vivo evaluation of histopathological alterations and trace metals estimation of small intestine in bisphenol A intoxicated rats. Canadian journal of Gastroenterology and Hepatology, 2019:1-8. [Impact Factor 2.055]
• Batool T., Akhtar T. Asghar A., Khawar M.B. and Sheikh N. 2019. Analysis of changes in hepatic expression and tissue architecture of heart and kidney in association with diet-induced obesity in Rattus norvegicus. J Biol Regul Homeost Agents, 33(1):221-224 [Impact Factor 1.469]
• Abdullah Abdo Albegali, Muhammad Shahzad, Muhammad Ikram Ullah, Saqib Mahmood, Maryam Rashid. Association of genetic polymorphism of PC-1 gene (rs1044498 Lys121Gln) with insulin resistant type 2 diabetes mellitus in Punjabi Population of Pakistan. Mol Genet Genomic Med. 2019 Aug;7(8):e775. [Impact Factor 2.448]
• Adnan Jehangir, Muhammad Shahzad, Khadija, Akbar Waheed. Zinc and Iron Complexes of Oleanolic Acid, (Oa) Attenuate Allergic Airway Inflammation in Rats. Inflammopharmacology. 2019 Dec;27(6):1179-1192. [Impact Factor 3.838]
• Fatima Ahsan, Arham Shabbir, Muhammad Shahzad, Aisha Mobashar. Amelioration of allergic asthma by Ziziphora clinopodioides via upregulation of aquaporins and downregulation of IL4 and IL5. Respiratory Physiology & Neurobiology. 2019 Aug;266:39-46. [Impact Factor 1.582]
• Umme Habiba Hassan, Alamgeer, Muhammad Shahzad. Amelioration of adjuvant induced arthritis in Sprague Dawley rats through modulation of inflammatory mediators by Ribes alpestre Decne. Journal of Ethnopharmacology 235 (2019) 460–471. [Impact Factor 3.414]
• Ambreen Malik Uttra, Alamgeer, Muhammad Shahzad. Ribes orientale: A novel therapeutic approach targeting rheumatoid arthritis with reference to pro-inflammatory cytokines, inflammatory enzymes and anti-inflammatory cytokines. Journal of Ethnopharmacology 237 (2019) 92–107. [Impact Factor 3.414]
• Saba Tariq, Mukhtiar Baig, Sundus Tariq. Muhammad Shahzad. Status of bone health and association of socio-demographic characteristics with Bone Mineral Density in Pakistani Females. Pak J Med Sci May - June 2019 Vol. 35 No. 3 [Impact Factor 0.834]
• Sabeen Arjumand, Muhammad Shahzad, Arham Shabbir, Muhammad Zubair Yousaf. Thymoquinone attenuates rheumatoid arthritis by downregulating TLR2, TLR4, TNF-α, IL-1, and NFκB expression levels. Biomedicine & Pharmacotherapy 111 (2019) 958–969 [Impact Factor 3.743]
• Maryam Rashid, Muhammad Shahzad, Saqib Mahmood, Khurshid Khan. Variability in the therapeutic response of Metformin treatment in patients with type 2 diabetes mellitus. Pak J Med Sci January - February 2019 Vol. 35 No. 1, [Impact Factor 0.834]
• Umme Habiba Hasan, Alamgeer, Muhammad Shahzad, Shah Jahan. Inhibitory effects of Clematis orientalis aqueous ethanol extract and fractions on inflammatory markers in complete Freund’s adjuvant‐induced arthritis in Sprague–Dawley rats Inflammopharmacology. 2019 Aug;27(4):781-797, [Impact Factor 3.838]
• Siddiqui Sara, Ashraf Komal, Malka M Samra, Muhammad Shahzad. Immunological and clinical evaluation of Triticum aestivum aeroallergens in asthmatic patients. SPG BioMed 2019,
• Aziz RS, Siddiqua A, Shahzad M, Shabbir A, Naseem N. Oxyresveratrol ameliorates ethanol-induced gastric ulcer via downregulation of IL-6, TNF-α, NF-ĸB, and COX-2 levels, and upregulation of TFF-2 levels. Biomed Pharmacother. 2019 Feb;110:554-560. [Impact Factor 3.743]
• Ambreen Malik Uttra, Alamgeer, Muhammad Shahzad, Arham Shabbir, Shah Jahan. Ephedra gerardiana aqueous ethanolic extract and fractions attenuate Freund Complete Adjuvant induced arthritis in Sprague Dawley rats by downregulating PGE2, COX2, IL-1β, IL-6, TNF-α, NF-kB and upregulating IL-4 and IL-10. Journal of Ethnopharmacology 224 (2018) 482–496 [Impact Factor 3.414]
• Hafiz Muhammad Ishaq, Imran Shair Mohammad, Muhammad Shahzad, Chaofeng Ma, Muhammad Asif Raza. Molecular Alteration Analysis of Human Gut Microbial Composition in Graves' disease Patients. Int J Biol Sci 2018; 14(11):1558-1570. [Impact Factor 4.067]
• Hina Aslam, Muhammad Shahzad, Arham Shabbir, Sabeen Irshad. Immunomodulatory Effect of Thymoquinone On Atopic Dermatitis. Mol Immunol. 2018 Sep;101:276-283. [Impact Factor 3.064]
• Asghar A., Akhtar T. and Sheikh N. 2018. Inquisition of variations in serum protein profile induced by fat rich diet in Rattus norvegicus. Punjab Univ. J. Zool. 33(1):28-33. [HEC recognized Y-Category]
• Yasir Arfat, Muhammad Asim Basra, Muhammad Shahzad, Kashif Majeed. 4miR-208a-3p Suppresses Osteoblast Differentiation and Inhibits Bone Formation by Targeting ACVR1. Molecular Therapy Nucleic Acids. Volume 11, 1 June 2018, Pages 323-336, [Impact Factor 5.919]
• Arham Shabbir, Syeda Amina Batool, Muhammad Irfan Basheer, Muhammad Shahzad, Kishwar Sultana. Ziziphora clinopodioides ameliorated rheumatoid arthritis and inflammatory paw edema in different models of acute and chronic inflammation. Biomedicine & Pharmacotherapy 97 (2018) 1710–1721., [Impact Factor 3.743]
• Adeela Fatima, Usman Aftab, Khaled A. Shaaban, Jon S. Thorson and Imran Sajid, BMC Microbiology, Spore forming Actinobacterial diversity of Cholistan Desert Pakistan: Polyphasic taxonomy, antimicrobial potential and chemical profiling, 2019,19:49 https://doi.org/10.1186/s12866-019-1414-x [Impact Factor 2.82]
• Hafiz Muhammad Ishaq, Muhammad Shahzad, Xiaokang Wu, Chaofeng Ma, Jiru Xu. Gut Microbe Analysis between Asthma Patients and Healthy Volunteers, in Shaanxi Province, Xi’an China. Pakistan Journal of Zoology vol. 50(1), pp 165-173, 2018., [Impact Factor 0.790]