Research Activities

Research Projects Completed

In last five years following research projects had been completed in Biochemistry department;

  • Association of hyper homocysteinemia with coronary artery disease independent of traditional risk factors
  • Comparison of CEA and CA 19-9 with CA 72-4 in patients with gastrointestinal carcinomas in localpopulation.
  • Correlation of serum ferritin and serum transferring receptor/Ferritin ratio with oxidized low density lipoproteins in ischemic heart disease.
  • Serum levels of HER-2/neu and estrogen in women with carcinoma of the breast and their correlation with body mass index.
  • Correlation of serum adiponectin and serum lipoprotein (a) in coronary artery disease.
  • Correlation of serum leptin and P-selectin in coronary artery disease.
  • Serum Zinc and copper concentrations in patients with carcinoma of prostate.
  • Correlation of serum zinc levels with aqueous humor and zinc levels in patients with senile cataract.
  • Correlation of plasma Selenium and osteopontin concentrations in patients with carcinoma of prostate.
  • Glutathione and G6PD in Oxidative stress in metabolic syndrome.
  • Role of Glutamic acid, Iron, and Homocysteine in neonates with hypoxic ischemic encephalopathy.
  • Molecular analysis of GALT gene in patients with Galactosemia.
  • Molecular Genetic Studies in Families with Autosomal Recessive Primary Microcephaly (MCPH) From Punjab.
  • Association of Levels of Serum Selenium with Anemia in Primary School Children.
  • Blood lead level and its correlation with biochemical parameters in city traffic police of Lahore.
  • Detection of TNF-A Gene Polymorphism (-308 G/A) in acne vulgaris patients.
  • Assessment of DNA Damage Due To Lead Exposure in Traffic Wardens of Lahore.
  • Evaluation of Trace Element Deficiency in Male Infertile Patients from Cholistan.
  • Linkage analysis of oculocutaneous albinism (OCA) in Pakistani families.
  • Association of Single Nucleotide Polymorphism of Interleukin-6 Receptor (IL-6R) gene with Rheumatoid Arthritis in patients from Pakistan.
  • 21. Estimation of Serum Trace Elements (Zn+2, Cu+2 and Fe+2) In Rheumatoid Arthritis.
  • 22. Steroidogenic Factor-1 (NR5A1) in 46-XY Individuals with Disorders of Sex Developments (DSDs).

Current/on going Research Projects
Following research projects are going on;

  1. CYP1B1 Mutations in Local Patients with Primary Congenital Glaucoma.
  2. 2. Comparison of serum calprotectin in type 2 diabetic and non-diabetic males with and without obesity and its correlation with HOMA_IR and HOMA-B.
  3. 3. Betatrophin levels in type 2 diabetic and non-diabetic males with and without obesity and its correlation with HOMA-IR, HOMA-B and Triglycerides.